Analysis system and method for obtaining stable state/transient state light diffusion characteristic

Abstract

The invention discloses an analysis method for obtaining stable state / transient state light diffusion characteristic, which belongs to the field of optical detection in biological and medical engineering science. The analysis method of the present invention utilizes easy-obtained optical parameters of each tissue in organism and light source parameters of optical detector, describes matrix of organism tissue structure and Monte Carlo model to calculate diffusion characteristic, employs a light transmission Monte Carlo method which is suitable for multi-voxel biological tissue, can be applied into organism with complicated three dimensional structure, and has higher accuracy and stability. The method sets two parameters of diffusion characteristic sampling frequency and sampling interval, introduces photon movement timing function into a recording module, and has characteristic of intelligently obtaining the stable state / transient state light diffusion characteristic. The invention also discloses a system for obtaining the stable state / transient state light diffusion characteristic, which includes a parameter input module, a tissue model input module, a diffusion characteristic calculation module, a diffusion characteristic recording module and a diffusion characteristic output module.

Description

technical field [0001] The invention relates to an optical detection method in the field of biomedical engineering, in particular to an analysis system and method for obtaining steady state / transient light diffusion characteristics. Background technique [0002] Compared with bioelectricity, PET, fMRI and other technologies that have been widely used in biological detection, optical technology has the advantages of non-invasive measurement, low cost, portability, high resolution, and can be used for disease prevention and treatment. potential emerging technologies. With the development of its application, people put forward higher requirements for the reliability and accuracy of the technology. To solve this problem, it is urgent to obtain the high-precision light diffusion characteristics of living organisms in actual optical detection, so as to provide a platform for the development and optimal design of instruments, the optimization of optical treatment schemes, and the ...

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Problems solved by technology

At present, the Monte Carlo software 'MCML' (S.L.Jacques and L.Wang. "Monte Carlo modeling of light transport in tissues, "in 1995 Proc OPTICAL-THERMAL RESPONSE OF LASER-IRRADIATED TISSUE Conf ., PP.73-99. and L. Wang, S.L. Jacques, and L. Zheng, "MCML--Monte Carlo modeling of light transport in multi-layered tissues," Comput. Methods. Programs. Biomed., vol.47 , pp.131-146, 1995.), can only calculate the steady-state diffusion characteristic parameters of cylindrical multi-layer biological tissue, which is a simplified method, such as figure 1 As shown, it cannot be applied to biological tissues that generally have complex structures, and the transient light diffusion properties cannot be calculated

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