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Traditional Chinese medicine compound recipe for treating chronic hepatitis-B and preparation method thereof

A chronic hepatitis B and compound technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of easy drug resistance and achieve the effect of treating chronic hepatitis B

Inactive Publication Date: 2009-07-29
BEIJING SUNHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the antiviral drugs used to treat hepatitis B at home and abroad mainly include interferon and lamivudine, but they are prone to drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 10 parts of Foliage Gallbladder, 8 parts of Liuyuexue, 8 parts of Astragalus membranaceus, and 6 parts of Salvia miltiorrhiza, crushed, mixed, decocted and extracted three times with water, each time the amount of solvent was 10 times, 8 times, 8 times, and the extraction time was 2 hours, 1 hour, 1 hour, filter, combine the filtrate, concentrate the filtrate under reduced pressure, and spray dry to obtain the active extract.

Embodiment 2

[0030] 15 parts of Foliage Gallbladder, 10 parts of Liu Yuexue, 10 parts of Astragalus membranaceus, 8 parts of Salvia Miltiorrhiza, crushed, mixed, decocted and extracted three times with water, each time the amount of solvent was 12 times, 8 times, 8 times, the extraction time was 2 hours, 1 hour, 1 hour, filter, combine the filtrate, concentrate the filtrate under reduced pressure, and spray dry to obtain the active extract.

Embodiment 3

[0032] 8 parts of Aoba bilibilis, 7 parts of Liuyuexue, 4 parts of Astragalus membranaceus, 4 parts of Salvia miltiorrhiza, crushed, mixed, decocted and extracted three times with water, each time the amount of solvent was 10 times, 8 times, 8 times, the extraction time was 2 hours, After 1.5 hours and 1.5 hours, filter, combine the filtrates, concentrate the filtrate under reduced pressure, and spray dry to obtain the active extract.

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PUM

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Abstract

The invention relates to a Chinese medicine compound prescription for treating chronic hepatitis B and a method for preparing the same. The Chinese medicine compound prescription consists of mile swertia, serissa foetida comm, astragalus root and radix salivae miltiorrhizae; the materials are decocted by water and extract to obtain a compound active extract. The Chinese medicine compound prescription has the protecting function on liver injury, can reduce the level of ALT and MDA of serum in liver, raise the activity of SOD of serum and has effect of treating hepatitis caused by bcg vaccine. The Chinese medicine compound prescription can be used for preparing a drug with the function of treating chronic hepatitis B.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a Chinese medicine compound preparation for treating chronic hepatitis B and a preparation method thereof. Background technique [0002] At present, about 2 billion people in the world have been attacked by hepatitis B virus (HBV), and 350 million of them have developed chronic HBV infection. Chronic hepatitis B can develop into liver cirrhosis and liver cancer, and about 1 million people worldwide die from HBV infection-related diseases every year. my country is a high-incidence area of ​​hepatitis B, about 50% of people have been infected with HBV, and chronic HBV carriers account for 9.75% of the national population. At present, the antiviral drugs used to treat hepatitis B at home and abroad mainly include interferon and lamivudine, but they are prone to drug resistance. Therefore, safe, effective and stable drugs have become ve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K9/08A61K9/10A61K9/20A61K9/48A61P1/16A61P31/20
Inventor 张树祥熊国裕
Owner BEIJING SUNHO PHARMA
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