Particle analyzer and particle analysis method

Abstract

The invention discloses a particle analyzer and a particle analysis method. The analyzer comprises a flow chamber through which a sample liquid containing particles flows, a drive unit which is used for driving the sample liquid to flow through the flow chamber, a light irradiation unit which is used for emitting specific spectra to the particles in the flow chamber, a magnification imaging unit and a feature extraction analysis unit, wherein the magnification imaging unit acquires particle images formed under the specific spectra, magnifies and then outputs the images to the feature extraction analysis unit; and the feature extraction analysis unit extracts image features, identifies and classifies the particles according to the features. The analysis method comprises the steps of driving the sample liquid containing the particles to flow through the flow chamber, emitting the specific spectra to the particles in the flow chamber, acquiring the particle images formed under the specific spectra, magnifying the images, extracting the image features, identifying and classifying the particles according to the features. Clinical diseases needing to depend on images for analysis can be accurately judged through the invention.

Description

technical field [0001] The invention relates to a particle analyzer, and also relates to a particle analysis method. Background technique [0002] Existing blood cell analyzers, urine analyzers, and other types of particle analyzers are based on flow cytometry. The basic principle of the existing particle analysis method based on flow cytometry is: first dilute and suspend particles such as blood cells and urine in liquid, and then use the principle of fluid focusing to wrap the sample liquid containing particles in a pure sheath In the liquid, the particles pass through the through hole of the square flow chamber one by one (that is, the detection area); the detection area is irradiated by the beam provided by the illumination system (usually a laser), and scattering occurs when the particles pass through this area Light or fluorescent signals (if the cells are labeled with fluorescent markers); the signal processing unit detects various optical signals generated by any pa...

AI Technical Summary

Problems solved by technology

[0003] The existing particle analysis methods have the following disadvantages: (1) The characteristics of each particle are marked with several optical signals, but the clinical judgment of some diseases (such as: leukemia) needs to rely on the image of the particle , these diseases cannot be accurately judged by existing particle analyzers; (2) Each measurement process can only obtain the overall characteristics of the tested sample without the individual characteristics of each particle, and often when the sample is abnormal Sometimes, doctors are more interested in some special particles, but they cannot further observe and analyze these special particles

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