Novel antibiotic substitute

A technology of antibiotics and substitutes, applied in the field of new antibiotic substitutes, can solve the problems of limited resources, unscientific formula, strong hygroscopicity, etc.

Active Publication Date: 2009-03-25
COFCO BEIJING FEED TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In recent years, researchers at home and abroad have found that organic acids, enzyme preparations, functional oligosaccharides, probiotics, Chinese herbal medicines and extracts, etc., can all play the role of antibiotic substitutes under specific conditions, but due to the existence of various However, the application of the above products is greatly limited, such as acidifiers and functional oligosaccharides have disadvantages such as strong hygroscopicity and easy caking, enzyme preparations and microecological preparations have poor thermal stability and are easily inactivated; Chinese herbal medicine additives There are disadvantages such as high cost, limited resources, unscientific formula, unstable quality, etc.

Method used

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Examples

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example 1

[0016] Formula: content per 1000 servings

[0017] Montmorillonite gel 0.1 parts

[0018] Sodium metasilicate pentahydrate 12 parts

[0019] Sodium carbonate 1.5 parts

[0020] Potassium carbonate 2.2 parts

[0021] Sodium selenite 0.2 parts

[0022] Brown sugar 5 parts

[0023] Rice bran 979 parts

[0024] Production process: (1) montmorillonite gel, sodium metasilicate pentahydrate, sodium carbonate, potassium carbonate and all sodium selenite and brown sugar, which account for 6.7% of the respective content in the formula, are dissolved in 310 One part of water is made into a uniform liquid, and the prepared liquid is mixed with 979 parts of rice bran while stirring. (2) Place the uniformly mixed rice bran in an environment with a temperature of 25°C and a relative humidity of 85% for aerobic solid fermentation for 7-15 days, during which the temperature is controlled at 30-60°C by overturning, and supplemented oxygen. (3) Dissolve the remaining 93.3% montmorillonit...

example 2

[0038] Formula: content per 1000 servings

[0039] Sodium metasilicate pentahydrate 13 parts

[0040] Sodium carbonate 1.3 parts

[0041] Potassium carbonate 2.4 parts

[0042] Sodium selenite 0.3 parts

[0043] Brown sugar 4 parts

[0044] Rice bran 979 parts

[0045] Production process: (1) Dissolve 0.7 parts of sodium metasilicate pentahydrate, 0.1 parts of sodium carbonate, 0.15 parts of potassium carbonate, 0.2 parts of sodium selenite, and 4 parts of brown sugar into 310 parts of water while stirring to make a uniform liquid , and mix the liquid made into 979 parts of rice bran while stirring. (2) Place the uniformly mixed rice bran in an environment with a temperature of 25°C and a relative humidity of 85% for aerobic solid fermentation for 7-15 days, during which the temperature is controlled and oxygen is increased by overturning. (3) Dissolve the remaining 12.3 parts of sodium metasilicate pentahydrate, 1.2 parts of sodium carbonate, and 2.25 parts of potassium...

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Abstract

The invention discloses a preparation for novel antibiotic substitute and a preparing art and mainly relates to the agricultural biotechnology and feed additive field. The preparation includes montmorillonite gel, sodium metasilicate, carbonate, reducing sugar, sodium selenite and rice bran. Adopting the solid aerobic biological fermentation, the preparation has simple art and fine stability. The preparation can improve animal healthy level and the resistance ability and anti-stress capability for pathogeny microbial beings through enhancing animal nonspecific and specific immunity ability, so as to improve animals food consumption, daily gain and food conversion ratio, ensure animals producing performance under the no antibiotic condition, and avoid the generation of antibiotic remain and drug-resistant strain in the animals production. The preparation can play an important role in improving the stockbreeding sustainable development and enhancing human healthy level.

Description

technical field [0001] The invention is a novel antibiotic substitute, which is mainly used for improving the immune function of animals, and mainly relates to the fields of agricultural biotechnology and feed additives. technical background [0002] With the intensification of the breeding industry and the improvement of animal production performance, the stress level of animals continues to increase, the resistance to various pathogenic microorganisms decreases, and they are often in clinical or subclinical pathological conditions, which affects the production potential and development of animals. In order to prevent diseases and improve economic benefits, it is common practice to add antibiotics and chemically synthesized drugs to feed. However, the use of antibiotics has led to the emergence of drug-resistant strains and even superbugs that can resist multiple antibiotics, and the quality of animal products has also been continuously reduced due to the problem of drug re...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P37/04A23K1/16A61K31/70A61K33/00A61K33/04A61K33/06A23K10/12A23K10/30A23K20/163A23K20/20A23K20/28
Inventor 宋金彩张树光但堂胜柯群
Owner COFCO BEIJING FEED TECH
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