Vitamin orally disintegrating tablet and preparation method thereof

Abstract

The invention provides a vitamin orally disintegrating tablet and a preparation method thereof; the medical prescription components comprise the combination of multiplex vitamins or single vitamin, a loading agent, a disintegrant, a sacarina and a lubricant, etc. The invention aims at providing the vitamin orally disintegrating tablet with simple technique and convenient taking, and is characterized in that the technical requirements are achieved by using disintegration technology and sacarina technology to make synergic action. The vitamin orally disintegrating tablet provided by the invention are rapidly disintegrated in the oral cavity into fine particles, so as to be beneficial to the dissolving and absorption of the vitamin, thus achieving the goal of effectively supplementing the vitamin needed by the human body in time. The preparation of the invention can be taken conveniently and is especially suitable for the people such as old people, children and the patients with some diseases who have swallowing difficulty and need to supplement vitamin, or in the special environment such as having no drinkable water in a journey and out of home.

Description

technical field [0001] The invention relates to a vitamin orally disintegrating tablet and a preparation method thereof. Background technique [0002] Vitamins are a kind of nutrients necessary to maintain human health. They are auxiliary components of the enzyme system in the human body, participate in a wide range of biochemical reactions in the human body, and regulate the metabolic functions of the human body. Although the amount required is very small, once the human body lacks vitamins, the metabolism will be lost. Balance, immunity decline, various diseases will take advantage of it. Conversely, clinically, when the human body is in a disease state, it usually lacks one or several vitamins, and vitamin supplementation has become a routine treatment for many. For example, colds, tonsillitis, and pharyngitis often require vitamin C and B vitamins, and oral ulcers often require vitamin B supplementation. 2 . [0003] Generally speaking, as long as the food structure i...

AI Technical Summary

Problems solved by technology

For example, the sale of currently commercially available vitamin AD drops (soft capsule type) is very good, and almost every infant needs to take it, but this product also has certain deficiencies

First, compared with orally disintegrating tablets, taking it is not convenient enough, because taking it still requires tools to cut or puncture

Second, the dosage is not accurate enough, because it is necessary to cut or puncture the tip of the soft capsule when using it, squeeze it and drop it into the mouth of infants or young children or milk, it is impossible to squeeze out all the contents, and sometimes even spray and leak

Third, the taste is not good enough. Perhaps when infants are young, their sense of taste is not yet fully developed, and they are willing to take vitamin AD drops; as they grow up, their sense of taste is gradually developed, and they may not like this taste and refuse to eat it.

Generally speaking, the more disintegrant is added, the faster the disintegration will be; however, if the content of disintegrant is too high, the tablet will be difficult to form, and even if it is formed, it will be fragile; if the content of disintegrant is too low, the disintegration will be slowed down, Failure to meet the technical requirements for orally disintegrating tablets to disintegrate within 1 minute

Under the same prescription and process conditions, the smaller the hardness and the greater the friability of the tablet, the faster the disintegration will be, but industrial production requires the tablet to maintain a considerable hardness and a small friability. accomplish