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Gel for ultrasonic phantom

An ultrasound and phantom technology, applied in applications, ultrasonic/sonic/infrasonic diagnosis, sonic diagnosis, etc., can solve the problems of ultrasonic characteristics fluctuations, bacterial reproduction has not been solved, etc., to achieve the effect of sufficient ultrasonic characteristics

Inactive Publication Date: 2008-12-03
TAKIRON CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Plus, the inevitable question about bacterial reproduction remains unanswered
Superphantoms made of hydrogels, which contain water, inevitably have problems with fluctuations in ultrasonic properties

Method used

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  • Gel for ultrasonic phantom
  • Gel for ultrasonic phantom
  • Gel for ultrasonic phantom

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0104] Polyols and polyisocyanates were prepared, each having a structure, molecular weight, and alkylene oxide (AO) segment corresponding to the structural formula numbers shown in Table 1 below, according to the corresponding parts shown in Table 1 section. Propylene carbonate as organogel swellable matrix and dibutyltin laurate as catalyst were mixed with polyols in the corresponding amounts in parts shown in Table 1. Thereafter, the obtained liquid mixture was mixed with polyisocyanate to prepare a material liquid having an OH / NCO of 2.7.

[0105] This material liquid was poured into a mold and reacted at 50° C. for 8 hours. In this way, a block polyurethane gel for ultrasonic phantom was obtained, which had EO / PO random copolymer segments with a EO / PO molar ratio of 1:1, and contained 50% by weight of propylene carbonate as Organogel swellable matrix.

[0106] For the obtained ultrasonic phantom, its density was checked with gel, and using a ring sound velocity meter [m...

Embodiment 2-5

[0112]The same procedure as in Example 1 was performed except that the parts of the amount of propylene carbonate as the organogel-swellable matrix were changed to 61.7 parts by weight, 99.6 parts by weight, 431.7 parts by weight and 1,048 parts by weight, respectively. Therefore, an ultrasound phantom gel containing 25% by weight of propylene carbonate (Example 2), an ultrasound phantom gel containing 35% by weight of propylene carbonate (Example 3), and an ultrasound phantom gel containing 70% by weight of An ultrasound phantom gel of propylene carbonate (Example 4), and an ultrasound phantom gel containing 85% by weight of propylene carbonate (Example 5).

[0113] In the same manner as in Example 1, the density, ultrasonic attenuation coefficient and ultrasonic propagation velocity of the gel for ultrasonic phantom were detected immediately after preparation, and the ultrasonic attenuation coefficient and ultrasonic propagation velocity were further detected after 8 months. ...

Embodiment 6

[0123] Polyols and polyisocyanates each having a structure, molecular weight, and alkylene oxide (AO) segment corresponding to the structural formula numbers shown in Table 3 below were prepared according to the amounts shown in Table 3 in parts. Propylene carbonate as an organogel swellable matrix and dibutyltin laurate as a catalyst were mixed with the polyol in the respective part numbers shown in Table 3. Thereafter, the obtained liquid mixture was mixed with polyisocyanate to prepare a material liquid having an OH / NCO of 4.0.

[0124] The liquid material was poured into a mold, and reacted at 50° C. for 8 hours. In this way, a block polyurethane gel for ultrasonic phantom was obtained, which had EO / PO random copolymer segments with an EO / PO molar ratio of 1:1, and contained propylene carbonate in an amount of 44% by weight As an organogel swellable matrix.

[0125] With this gel for ultrasound phantom, in the same manner as in Example 1, the density, ultrasound attenuat...

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Abstract

It is intended to provide a gel for an ultrasonic phantom which has favorable ultrasonic characteristics that can be sustained over a long period of time without alteration and is free from bacterial contamination, denaturation, putrefaction, etc. Namely, a gel for an ultrasonic phantom which comprises a segmented polyurethane gel having alkylene oxide segments, which are mostly or entirely in the form of a liquid at room temperature, and a nonvolatile organic gel expansion medium, which would not participate in the reaction of the urethane, contained therein. Owing to the nonvolatile organic gel expansion medium, the liquid segments, etc. are maintained in the spread state and thus the spaces among the segments are enlarged, which brings about favorable ultrasonic characteristics such as ultrasonic attenuation rate and transmission speed. Since the content of the expansion medium shows no temporal change, these favorable ultrasonic characteristics are maintained over a long period of time. Because of containing the organic gel expansion medium, the gel for an ultrasonic phantom is free from bacterial contamination, denaturation, putrefaction, etc.

Description

technical field [0001] The present invention relates to an ultrasonic phantom (living tissue model) gel suitable for purposes such as medical ultrasonic research for ultrasonic examination of body parts, calibration of ultrasonic diagnostic instruments, and skill training for doctors and technicians Wait. Background technique [0002] Hydrogels of gel materials for phantoms have been studied, such as gels containing agar or gelatin as a base material, gels containing glucomannan contained in konjac as a base material (Patent Document 1), including A gel containing acidic water-containing poly(vinyl alcohol) as a base material (Patent Document 2), a gel containing water-swellable urethane resin as a base material (Patent Document 3), and a gel containing water-containing A water-absorbent resin-based gel (Patent Document 4). The use of some of these hydrogels in the research of medical ultrasound, the calibration of ultrasonic diagnostic instruments, and the skill training ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B8/00G01N29/28
CPCA61B8/00G09B23/285A61B8/587G01N29/28
Inventor 敷波保夫蔦薰
Owner TAKIRON CO LTD
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