Acetolactate synthetase AHAS restrainer combination

Abstract

The invention relates to an inhibitor compound for acetolactate synthetase AHAS, which is indoline diketone compound (I); wherein, R1 is H or CH3, R2 is O or N-OH, R3 is F, Cl, Br, I, CH3, OCH3, NO2, SO3H, OCF3 or CF3, R4 is F, Cl, Br, I, CH3 or OCH3. The inhibitor compounds for acetolactate synthetase has the advantages of having herbicidal activity, having inhibiting action upon arabidopis thaliana aceto-lactic acidsynzymeas well as upon growth of rape root and being used for designing new environmentally friendly herbicide molecule.

Description

technical field The present invention relates to a new class of small-molecule inhibitors mainly based on indolinediones with acetolactate synthase AHAS as the target, and specifically relates to the effect of this type of compound on Arabidopsis thaliana (Arabidopsis thaliana) in vitro. ) inhibitory activity of AHAS, and the inhibitory activity of these compounds on rapeseed root growth in vivo (in vivo). technical background Since entering the 21st century, food and environmental issues facing mankind have become increasingly prominent. On the one hand, the total population of the world continues to grow, and the global food supply is becoming more and more tense; on the other hand, the serious problems caused by chemical pollution in the natural environment on which human beings depend have also become a problem that cannot be ignored. Therefore, it has become an urgent historical task to ensure the maximum food supply while minimizing the negative impact on the environm...

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Problems solved by technology

However, there has never been any literature reporting that such compounds have AHAS inhibitory effects and herbicidal activity

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