Gene chip for gynecologic malignant tumor early screening and detection method thereof
A malignant tumor and gene chip technology, which is applied in the field of gene chip and its detection for the early screening and diagnosis of common gynecological malignant tumors, can solve the problems of inability to conduct general surveys, early diagnosis of tumor patients, poor specificity, etc., and achieve simple sampling and maintenance Consistency, easy general sieving effect
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Embodiment 1
[0034] Blood samples from several cancer patients were collected, and prepared into oligonucleotide gene chips by Gene Company according to the aforementioned requirements.
Embodiment 2
[0036] Take 5ml of patient A's blood and extract a blood gene sample, and hybridize the sample gene with the oligonucleotide gene chip. The hybridization results obtained from the detection show that the expression of VEGFA (M27281), IGF1 (NM_000618), and LTA (NM_000595) in A's blood is up-regulated , which means that patient A is likely to suffer from breast cancer.
Embodiment 3
[0038] Take 5ml of patient B's blood and extract a blood gene sample, and hybridize the sample gene with the oligonucleotide gene chip. The hybridization results obtained by detection show that the expression of RASSF1 (NM_007182) is down-regulated and the expression of CD44 (X55150) is up-regulated in B's blood, which means that Patient B is likely to have ovarian cancer.
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