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Apparatus and method for coupling implanted electrodes to nervous tissue

A technology of electrical coupling and electrodes, applied in the field of nanoscale topology, can solve the problems of shortened battery life, increased cost, and increased energy consumption

Inactive Publication Date: 2008-07-16
KONINKLIJKE PHILIPS ELECTRONICS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, increasing the stimulation magnitude results in increased costs due to increased power consumption and reduced lifespan of the implanted battery
Shorter battery life also means more frequent battery replacements, necessitating more surgical procedures to replace batteries

Method used

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  • Apparatus and method for coupling implanted electrodes to nervous tissue
  • Apparatus and method for coupling implanted electrodes to nervous tissue
  • Apparatus and method for coupling implanted electrodes to nervous tissue

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Embodiment Construction

[0024] As described herein, the devices and methods of the present invention advantageously increase neuron-electrode coupling efficiency by locally reducing the gap between the nerve cell and the electrode surface. The use of columnar structures protruding from the electrode surface reduces the gap between nerve cells and the electrode surface to allow and facilitate interfacing of neural tissue in, for example, implantable neurostimulating medical devices. The invention can be extended to any application requiring electrical coupling to single or multiple cells in order to sense or stimulate cells. More specifically, the present invention proposes the use of columns with a very small surface area (eg, small diameter columns) to avoid attachment of glycan coating molecules to the ends or top, which would prevent direct contact between the column and the cell membrane. Furthermore, the present invention suggests the use of an overall low density of pillars (eg, less than 10 pi...

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PUM

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Abstract

An apparatus and method for improving electrical contact between an implanted device (10) for recording or stimulating neuronal activity and surrounding tissue (12) (e.g., brain tissue, nerve fibers, etc.). In an exemplary embodiment, a nanometer sized topographic structure (36, 136) (e.g., a nanometer scale pillar) is processed for electrical connection with a corresponding electrode (30, 32) of the implanted device (10). The nanometer scale topographic structure (36, 136) bridges a gap (26) between the implanted device (10) and surrounding tissue (12), thus improving neuron-electrode coupling therebetween. The present disclosure can also be extended to any application where capacitive coupling to single or multiple cells (20) can be used for sensing and / or stimulation thereof.

Description

technical field [0001] The present invention generally relates to topologies extending from implantable devices for electrical stimulation and / or detection of biological tissue. In particular, the present invention relates to nanoscale topologies extending from electrodes of implantable medical devices to improve neuron-electrode coupling. Background technique [0002] Electrodes are implanted long-term in the body to stimulate nerves and muscle tissue. For example, such chronically implanted electrodes are used in pacemakers, for deep brain stimulation in Parkinson's disease, and for functional electrical stimulation in the paralyzed. Similar chronically implanted electrodes can also record neural or muscle activity by recording action potentials or field potentials (e.g., for controlling prostheses and for closed-loop systems for deep brain stimulation (DBS)). [0003] Because of the trauma that occurs during electrode implantation, there is often an acute inflammatory r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/05A61N1/36A61B5/04
CPCA61N1/0551A61N1/0531A61N1/0543A61B5/04001B82Y15/00A61B5/6805A61N1/0529A61N1/0534A61B5/24
Inventor M·默茨Y·波诺马廖夫R·皮杰宁博格
Owner KONINKLIJKE PHILIPS ELECTRONICS NV
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