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Traditional Chinese medicinal composition for treating hepatitis and its preparation

A technology of composition and traditional Chinese medicine, which is applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of toxic and side effects, methods and drugs lacking special effects, etc.

Active Publication Date: 2011-07-27
ZHEJIANG WECOME MEDICINE IND +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment drugs for the advanced stage of early liver cirrhosis mainly include colchicine, prostaglandin E (PGE), interferon (Interferon), penicillinamine, and Malotile (Malotile), but Western medicine at home and abroad still does not treat it. Lack of effective methods and drugs
[0006] Among the above-mentioned drugs currently used in the treatment of liver diseases, most of the drugs have not achieved the expected clinical effect in clinical practice. Due to the limitations of western medicines against liver fibrosis, liver cirrhosis, and chronic hepatitis, most of them have toxic and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Astragalus 20g, Pueraria 15g, Bupleurum 15g, Ganoderma lucidum 8g, Radix Paeoniae Rubra 15g, Turtle Shell 15g, Salvia miltiorrhiza 15g, Panax notoginseng 8g, Chicken bone grass 15g, Phyllostachys foliage 20g

[0035] Add 8 times the amount of water to extract the turtle shell and Ganoderma lucidum 3 times, 3 hours each time, filter, combine the filtrate, and set aside; add 8 times the amount of 70% ethanol to extract 3 times, 1 hour each time , filter, combine the filtrates, recover ethanol under reduced pressure at 60°C, and set aside; add 8 times the amount of water to extract 3 times with 8 times the amount of water, and filter the filtrate with the aforementioned The two extracts were combined, concentrated to a thick paste with a relative density of 1.30-1.35 (50°C), dried under reduced pressure (60°C, -0.08Mpa), crushed into fine powder, added an appropriate amount of dextrin, mixed evenly, and added 60% The ethanol solution is used as a wetting agent, granulated ...

Embodiment 2

[0037] Astragalus 20g, Pueraria 6g, Bupleurum 6g, Ganoderma lucidum 5g, Chishao 6g, Turtle shell 6g, Salvia miltiorrhiza 10g, Panax notoginseng 5g, Chicken bone grass 6g, Phyllostachys foliage 20g

[0038] Extract the turtle shell and Ganoderma lucidum with 8 times the amount of 70% ethanol for 3 times, 3 hours each time, filter, combine the filtrate, and set aside; Add 8 times the amount of 70% ethanol to the beads and extract 3 times, each time for 1 hour, filter, combine the filtrates, recover the ethanol under reduced pressure at 60°C, and set aside; combine the filtrates, concentrate to a thick paste with a relative density of 1.30-1.35 (50°C) , dried under reduced pressure (60°C, -0.08Mpa), pulverized into fine powder, added lactose and starch in appropriate amount, mixed evenly, granulated, dried, added magnesium stearate, mixed evenly, pressed into tablets, coated to obtain tablets agent.

Embodiment 3

[0040] Astragalus 10g, Pueraria root 10g, Bupleurum 10g, Ganoderma lucidum 10g, Chishao 10g, Turtle shell 10g, Salvia miltiorrhiza 10g, Panax notoginseng 10g, Chicken bone grass 10g, Phyllostachys 10g

[0041] Extract the turtle shell and ganoderma lucidum with 8 times the amount of water for 3 times, each time for 3 hours, filter, combine the filtrate, and set aside; Extract 3 times with 8 times the amount of water, each time for 1 hour, filter, combine the filtrate, and set aside; combine the filtrate, concentrate it into a clear paste, add ethanol to make the alcohol content reach 65%, let stand and refrigerate overnight, take the supernatant, reduce Press to recover ethanol, add appropriate amount of sodium saccharin, essence, sodium benzoate, sorbitol, and Tween-80, stir and mix evenly, add water to constant volume, and pack separately to obtain oral liquid.

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Abstract

The present invention discloses a Chinese medicine compound for curing hepatic disease and a preparation method thereof. The Chinese medicine compound is made from according to milk veteh, kudzuvine root, Chinese thorowax, ganoderma, red paeonia, turtle shell, salvia miltiorrhiza, gynura segetum, canton love-pea vine and leafflower according to a certain weight portion. The present invention can be made into any common dosage form. The medicine compound provided by the present invention has the efficacy of replenishing qi and relieving liver-qi, invigorating blood circulation and softening hard masses, which is used to cure hepatitis, hepatic fibrosis, hepatocirrhosis and other hepatic diseases.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating liver diseases and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Chronic hepatitis refers to a chronic inflammatory disease of the liver with a course of more than half a year. Liver fibrosis refers to abnormal hyperplasia of fibrous connective tissue in the liver, which is mostly caused by persistent liver injury or the presence of stimulating factors that promote fibrosis. Liver cirrhosis is a chronic, progressive and diffuse change in the liver caused by various reasons. Early liver cirrhosis refers to no specific clinical symptoms or signs, no obvious abnormalities in liver function tests, but obvious changes in liver histology. pathological changes. Chronic hepatitis B is a major risk factor for liver fibrosis, liver cirrhosis, liver cancer, and liver failure; mild liver fibrosis is called fibrou...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K9/16A61P1/16A61K35/56A61K35/586
Inventor 张保献
Owner ZHEJIANG WECOME MEDICINE IND
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