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Medicine or sanitary product containing licorice flavone extraction for oral cavity

An extract, the technology of licochalcone, is applied in the field of oral medicine or oral hygiene products containing licorice flavonoid extract, which can solve the problem of no compound

Inactive Publication Date: 2008-03-26
HAWLEY & HAZEL CHEMICAL CO (ZHONGSHAN) LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no compound licochalcone A (Licochalone A, 5-(1,1-Dimethylallyl)-4,4'-dihydroxy-2-methoxychalcone) of chemical formula (1) in the prior art as an active ingredient in the treatment of oral cavity There is no report on the disease, and there is no application of the compound in the preparation of anti-halitosis, anti-caries oral medicine or oral care products and in the preparation of anti-gingivitis, anti-plaque, tooth sensitivity, anti-calculus, and / or tooth enlargement Reports on the application of Bai's oral medicine or oral care products

Method used

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  • Medicine or sanitary product containing licorice flavone extraction for oral cavity
  • Medicine or sanitary product containing licorice flavone extraction for oral cavity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1: Application of total flavonoid extract of Glycyrrhiza inflata in toothpaste formulation

[0070] Toothpaste formula 1 of the total flavonoid extract of licorice inflating fruit:

[0071] ingredients

[0072] Toothpaste formula 2 of licorice flavonoids total extract:

[0073] ingredients

[0074] Toothpaste formula 3 of licorice flavonoids extract:

[0075] ingredients

[0076] Toothpaste formula 4 of licorice flavonoids total extract:

[0077] ingredients

[0078] Toothpaste formula 5 of the total flavonoid extract of licorice inflating fruit:

[0079] ingredients

[0080] Glycerin

[0081] Toothpaste formula 6 of licorice flavonoids total extract:

[0082] ingredients

[0083] Toothpaste formula 7 of total flavonoid extract of Glycyrrhiza inflata:

[0084] ingredients

[0085] Toothpaste formula 8 of total flavonoid extract of licorice inflating fruit:

[0086] in...

Embodiment 2

[0088] Embodiment 2: the application of licochalcone A in toothpaste formula

[0089] Licochalcone A Toothpaste Formula 1:

[0090] ingredients

Content (mass percentage, %)

Licochalcone A

0.0005-20

Friction agent

10-30

moisturizer

50-69

water, spices, seasonings

Appropriate amount

[0091] Licochalcone A Toothpaste Formula 2:

[0092] ingredients

Content (mass percentage, %)

Licochalcone A

5

silica

30

Glycerin

5

Sorbitol

50

water, spices, seasonings

Appropriate amount

[0093] Licochalcone A Toothpaste Formula 3:

[0094] ingredients

Content (mass percentage, %)

Licochalcone A

0.001

silica

10

Sorbitol

69

water, spices, seasonings

Appropriate amount

[0095] Licochalcone A Toothpaste Formula 4:

[0096] ingredients

Cont...

Embodiment 3

[0107] Example 3: Application of the flavonoids total extract of Glycyrrhiza inflata in mouthwash formula

[0108] Mouthwash formula 1

[0109] ingredients

Content (mass percentage, %)

Glycyrrhiza flavonoids extract PT-84

0.0005-20

water

70-94

other additives

Appropriate amount

[0110] Mouthwash formula of total extract of licorice flavonoids

[0111] ingredients

Content (mass percentage, %)

Glycyrrhiza flavonoids extract PT-84

5

water

80

Pluronic

3.00

other additives

Appropriate amount

[0112] Mouthwash formula 3

[0113] ingredients

Content (mass percentage, %)

Glycyrrhiza flavonoids extract PT-84

0.001

water

94

alcohol

5.00

other additives

Appropriate amount

[0114] Mouthwash formula of total extract of flavonoids of inflated licorice 4

[0115] ...

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PUM

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Abstract

The present invention relates to a compound licochalcone A (5-(1,1-dimethylallyl)-4,4'-dihydroxy-2-methoxychalcone) and glycyrrhiza inflate betal flavone extract, glycyrrhiza glabra Li flavone extract and glycyrrhiza kansuensis changet peng flavone extract containing said licochalcone A. Said invention also provides the application of licochalcone A and above-mentioned flavone extracts or their mixture in preparation of medicine for curing oral diseases, such as halitosis, caries and gingivitis, reducing calculus and dental plaque and whitening tooth, etc.

Description

1. Technical field [0001] The invention belongs to the technical field of medicines, and relates to the inhibitory effect of Licochalone A (5-(1,1-Dimethylallyl)-4,4'-dihydroxy-2-methoxychalcone) on oral cavity main pathogenic bacteria, As well as the application in the preparation of oral medicine or oral care products for inhibiting bad breath, preventing dental caries, reducing dental plaque, reducing gingivitis, removing tooth sensitivity, anti-calculus, and / or teeth whitening. 2. Technical background [0002] Common oral diseases in humans include dental caries and periodontal disease. Caries is a chronic bacterial disease that occurs in the hard tissue of the tooth, manifested as changes in color, shape, and quality of the hard tissue of the tooth. The clinical symptoms of periodontal disease are gingival bleeding, pus discharge, tooth loosening, alveolar bone resorption and periodontal pocket formation. Periodontal disease is also one of the leading causes of tooth ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K36/484A61K9/20A61K9/68A61K9/70A61K9/00A61Q11/00A61P1/02
CPCA61K8/35A61Q11/00A61K36/484A61K8/97A61K8/9783A61P1/02
Inventor 施瑶
Owner HAWLEY & HAZEL CHEMICAL CO (ZHONGSHAN) LTD
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