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Medicine for swelling and relieving pain and its preparation method and application

A technology for reducing swelling and relieving pain and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, non-central analgesics, etc., and can solve problems such as backward production technology, backward wanhua oil formulations, and quality control indicators that cannot be monitored.

Inactive Publication Date: 2011-02-02
广东中大南海海洋生物技术工程中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the formulation of Wanhua Oil is backward and has the following disadvantages: (1) it is still produced by oil soaking process in production, the production technology is backward, it will pollute the skin and clothes, and the scientific and technological content is insufficient; (2) it lacks research on effective material basis, quality control The indicators cannot monitor the quality, and the product can only be used in Guangdong and Guangxi regions, and it is difficult to promote it to the whole country, let alone enter the international market, which seriously restricts its due development prospects and cannot meet the requirements of modernization of traditional Chinese medicine.

Method used

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  • Medicine for swelling and relieving pain and its preparation method and application
  • Medicine for swelling and relieving pain and its preparation method and application
  • Medicine for swelling and relieving pain and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment one: the ointment of the medicine for reducing swelling and relieving pain described in the present invention

[0041] Weigh the raw materials (weight: kg) according to the following ratio:

[0042] Double-sided needle 200 safflower 100

[0043] Panax notoginseng 100 Peony bark 10

[0044] Chuanwu 100 Turpentine 10

[0045] Camphor 5 Menthol 2.5

[0046] Borneol 5 Cinnamon Oil 5

[0047] Its preparation method is to carry out according to the following steps:

[0048] A) Take Liangmianzhen, Panax notoginseng, and Shengchuanwu, grind them into 20-mesh coarse powder, and mix them with safflower for supercritical carbon dioxide extraction. The extraction parameters are extraction temperature 40-50°C, extraction pressure 23-29MPa, and analytical pressure 3 ~9MPa, analysis temperature 35~45℃, carbon dioxide flow rate 250L / h, extraction time 2~4 hours, the relative density of the obtained extract is adjusted to 1.20 with ethanol, and put it in a clean containe...

Embodiment 2

[0051] Embodiment two: the cataplasm of the medicine of reducing swelling and relieving pain described in the present invention

[0052] Weigh the raw materials (weight: kg) according to the following ratio:

[0053] LMZ 100 Safflower 50

[0054] Panax notoginseng 50 Moutan bark 5

[0055] Chuanwu 50 Turpentine 5

[0056] Camphor 2.5 Menthol 1.75

[0057] Borneol 2.5 Cinnamon Oil 2.5

[0058] Its preparation method is carried out according to the current conventional preparation method of cataplasm: the water-soluble high molecular polymer is used as the matrix skeleton material, and the extract or powder of the above-mentioned Chinese herbal medicine raw materials is compounded.

Embodiment 3

[0059] Embodiment three: the gel of the medicine for reducing swelling and alleviating pain according to the present invention

[0060] Weigh the raw materials (weight: kg) according to the following ratio:

[0061] Double-sided needle 300 safflower 150

[0062] Panax notoginseng 150 Peony bark 15

[0063] Chuanwu 150 Turpentine 15

[0064] Camphor 7.5 Menthol 3.75

[0065] Borneol 7.5 Cinnamon Oil 7.5

[0066] Its preparation method is carried out according to the current conventional gel preparation method: the extract of the above-mentioned Chinese herbal medicine raw material and a suitable matrix are made into a semi-solid or thick liquid preparation with gel properties.

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Abstract

The invention relates to a drug combination for detumescence and acesodyne and in particular to a drug combination for detumescence and acesodyne, which is made from the raw material of Chinese herbal medicines of plants, and the preparation method and the application of the drug combination. The drug combination for detumescence and acesodyne of the invention consists of ten Chinese herbal medicines of a peony bark, a pricklyash root, a safflower, a root of pseudo-ginseng, a Szechwan aconite, a terebinth, a borneol, a camphor, cinnamon oil and menthol. The invention has the efficacies of activating blood circulation, dispersing blood stasis, extending tract, activating collateral flow, detumescence and acesodyne; the external application can directly remedying partial ill parts; the drugefficacy penetrates quickly, and the stasis, the turgescence and the ache are eliminated fast; the drug combination is a good external anodyne salve for remedying the trauma of muscle, tendon, and parenchyma and the turgescence and the ache which are caused by the bone arthropathy and belong to blood stasis, retardarce and inside invading by cold-dampness.

Description

technical field [0001] The invention relates to a pharmaceutical composition for reducing swelling and relieving pain, in particular to a medicine for reducing swelling and relieving pain made from Chinese herbal medicines, as well as its preparation method and application. Background technique [0002] Soft tissue injuries and bone and joint lesions in orthopedics and traumatology are often characterized by local swelling and pain, which is one of the common pain syndromes in traditional Chinese medicine. It is often caused by improper exercise, bruises, work-related injuries and rheumatic tendon injuries. Its pathogenesis is summed up and always belongs to blood stasis internal resistance, and cold-damp attack arrives, and meridians are obstructed. Traditional Chinese medicine believes that "pain means no flow, and flow means no pain". In orthopedics, soft tissue injuries, commonly known as "injuries to tendons", are the most common diseases in traumatology. Soft tissue...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/714A61P29/00A61P19/08A61K31/045A61K31/125
Inventor 徐安龙荆琛峰黄静贤梁东
Owner 广东中大南海海洋生物技术工程中心有限公司
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