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Chinese medicine prepn for treating arrhythmia and its prepn process and quality control method

A technology of traditional Chinese medicine preparations and arrhythmia, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc. It can solve the problems of easy moisture absorption and deterioration, affecting the disintegration of preparations, the dissolution of active ingredients, and large dosages.

Active Publication Date: 2007-12-19
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the actual clinical use process, it is found that: the Chinese medicine extract powder made into granules, tablets, and capsules is easy to absorb moisture and deteriorate, which affects the disintegration of the preparation and the dissolution of the active ingredients; in addition, due to the content of the active ingredients, these three The dose required by this preparation dosage form is relatively large, and it is difficult for patients to take it; that is to say, the existing dosage form cannot fully meet the needs of both doctors and patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0063] Embodiment 2 of the present invention: Codonopsis 270g, Polygonatum 360g, Radix Notoginseng 54g, Amber 36g, Gansong 180g; Gansong is added 10 times of water, soaked for 4 hours, distilled for 6 hours, collected volatile oil, the distilled aqueous solution and medicinal residues respectively Collect it in another device; crush Panax notoginseng into coarse powder, reflux extract with 3 times the amount of 95% ethanol for 3 times, each time for 1 hour, filter, collect the dregs in another device, combine the filtrate, recover ethanol from the filtrate, and concentrate under reduced pressure to 60°C The clear ointment with a relative density of 1.05 is set aside; the other three flavors such as Panax notoginseng, Gansong dregs and Codonopsis pilosula, etc., add 12 times the amount of water and decoct for 3 hours, combine the decoction and the above-mentioned distilled aqueous solution, filter, and concentrate the filtrate to 60 For the clear ointment with a relative density...

Embodiment 3

[0064] Embodiment 3 of the present invention: Codonopsis 270g, Polygonatum 360g, Radix Notoginseng 54g, Amber 36g, Nardinus 180g; Nardinus 15 times of water, distilled for 2 hours, collected volatile oil, and the distilled aqueous solution and medicinal residues were collected separately; Grind Panax notoginseng into coarse powder, reflux extract with 8 times the amount of 65% ethanol for 3 hours, filter, collect the dregs in another device, combine the filtrate, recover ethanol from the filtrate, concentrate under reduced pressure to a clear paste with a relative density of 1.20 at 60°C, and set aside ; Panax notoginseng, Gansong dregs and Codonopsis pilosula, etc., add water to decoct 3 times, each time add 8 times the amount of water to decoct, each time for 1 hour, combine the decoction and the above-mentioned distilled aqueous solution, filter, and concentrate the filtrate To the clear ointment with a relative density of 1.30 at 60°C, add ethanol to make the alcohol conten...

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PUM

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Abstract

The present invention discloses one kind of Chinese medicine preparation for treating arrhythmia and its preparation process and quality control method. The Chinese medicine preparation is oral liquid prepared with five kinds of Chinese medicinal materials, including Dangshen, solomoseal, notoginseng, amber and spikenard. The quality control method for the Chinese medicine preparation includes the thin layer discrimination of notoginseng and spikenard, the checking of relative density and pH value, and the measurement of notoginseng. The Chinese medicine preparation has the functions of invigorating qi, nourishing yin, eliminating palpitate and restoring pulse. It is used in treating arrhythmia, ventricular premature beat and other cardiac and cerebral vascular diseases, and has the features of simple preparation process, fast acting, high curative effect, etc.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and its preparation method and quality control method, in particular to a traditional Chinese medicine preparation for treating arrhythmia and its preparation method and quality control method. Background technique [0002] Arrhythmia is one of the common and frequently-occurring diseases of cardiovascular disease, which seriously endangers the health of people, especially the middle-aged and elderly people. Therefore, it has long been a hot topic that the medical community has focused on and devoted to research and solution. On April 9, 2003, the Chinese Patent Gazette published the patent application of "a traditional Chinese medicine for treating arrhythmia and its preparation method" declared by the applicant in the name of employee Comrade Yang Ximing, and the publication number is 1408389. It uses Codonopsis pilosula, sealwort, notoginseng, amber and nard pine as raw materials to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P9/06A61K35/10
Inventor 赵涛
Owner SHANDONG BUCHANG PHARMA
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