Compound chitosan iodide film coating agent for preventing and controlling mammitis of cow and sheep

A technology of iodized chitosan and mastitis, applied in the field of compound iodized chitosan coating agent and its preparation, can solve the problems of slow effect, residue, milk antibiotic residue, etc., and achieves convenient use, low price, Good antibacterial effect

Inactive Publication Date: 2007-11-28
史义林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Nowadays, the treatment of mastitis adopts methods such as antibiotics, traditional Chinese medicine gavage and external application; in terms of prevention, methods such as maintaining environmental sanitation, strengthening the management of milking and milking staff, rationally configuring rations and teat dipping are used; but the above prevention The treatment methods all have shortcomings: there will be residues in the treatment with antibiotics, which will cause the waste of milk; there will be no residues in the treatment of traditional Chinese medicine, but the effect is slow
Some medicated bath products currently on the market add certain antibiotic ingredients, resulting in antibiotic residues in the milk; there are also some ingredients that add film-forming agents such as PVP,

Method used

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  • Compound chitosan iodide film coating agent for preventing and controlling mammitis of cow and sheep

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Effect test

Embodiment 1

[0022] Embodiment 1 (lactation period)

[0023] The compound iodized chitosan coating agent of the present invention preventing and treating bovine and sheep mastitis is formulated by following components (weight components)

[0024] Formula: chitosan deacetylation degree 90%, 100 mesh, 1g;

[0025] 40g of dandelion, 20g of dandelion and 40g of forsythia are 10ml.

[0026] Povidone-iodine 0.2g (available iodine is 0.02%)

[0027] Propylene glycol 2ml; Tween-20 0.1ml;

[0028] Glacial acetic acid 1ml, add water to dissolve to 100ml.

[0029] The technological process of preparation method is:

[0030] (1) Dissolve chitosan in 50ml of water, add 1ml of glacial acetic acid, and stir thoroughly; add 2ml of propylene glycol and 0.1ml of Tween-20, and dissolve completely.

[0031] (2) Mix dandelion, rehmannia, and forsythia according to the formula, add water and reflux for 30 minutes to 1 hour, and extract volatile oil. The remaining medicinal residues were decocted twice, ea...

Embodiment 2

[0034] Embodiment 2 (lactation period)

[0035] Formula: chitosan deacetylation degree 95%, 100 mesh, 1g

[0036] 60g of dandelion, 30g of dandelion and 60g of forsythia are 15ml.

[0037] Povidone iodine 0.1g (available iodine is 0.01%)

[0038] Propylene glycol 2ml; Tween-20 0.1ml;

[0039] Glacial acetic acid 1ml, add water to make up to 100ml.

[0040] Preparation method: with embodiment 1.

Embodiment 3

[0041] Embodiment 3 (dry period)

[0042] Formula: chitosan deacetylation degree 95%, 100 mesh, 2g

[0043] 40g of dandelion, 20g of dandelion and 40g of forsythia are 10ml.

[0044] Povidone-iodine 0.4g (available iodine is 0.04%)

[0045] Propylene glycol 4ml; Tween-20 0.2ml;

[0046] Glacial acetic acid 1ml, add water to dissolve to 100ml.

[0047] Preparation method: with embodiment 1

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Abstract

The present invention discloses one kind of compound iodized chitosan filming agent for preventing and treating mammitis of cow and ewe and its preparation process, and aims at providing filming agent with reasonable recipe, easy preparation, low cost and high curative effect. The compound iodized chitosan filming agent has the components, including chitosan 1-5 wt%, dandelion 3-20 wt%, Viola yedoensis 1.5-10 wt%, forsythia 3-20 wt%, polvidone iodine 0.02-1 wt%, propylene glycol 0.5-4 wt%, Tween-20 0.1-4 wt%, glacial acetic acid 0.5-2 wt%, and water 50-90 wt%. Its preparation process includes the following steps: 1. dissolving chitosan in water, and adding glacial acetic acid, propylene glycol and Tween-20; 2. extracting volatile oil with the Chinese medicinal materials, decocting, filtering, etc to obtain Chinese medicine extractum; 3. dissolving polvidone iodine in water; and 4. adding the extractum, the polvidone iodine solution into the chitosan solution, and adding water.

Description

technical field [0001] The invention relates to a compound iodized chitosan coating agent for preventing and treating bovine and sheep mastitis and a preparation method thereof, belonging to the technical field of veterinary medicine. Background technique [0002] Mastitis is one of the common diseases of cattle and sheep, which is very harmful to livestock production; the infection route of mastitis is usually through the nipple orifice invasion or through blood, lymphatic infection, often caused by unskilled milking techniques, poor milking clean, unclean breasts, and trauma to breasts and nipples caused by bacterial infection. Mastitis will affect the health of cattle and sheep, and reduce economic income; there are about 220 million dairy cows in the world at present, and about 1 / 3 of them suffer from various types of mastitis. The loss is as high as 300 billion yuan. [0003] Pathogen infection is the main cause of mastitis in dairy cows, and the main pathogenic bacte...

Claims

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Application Information

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IPC IPC(8): A61K36/86A61K9/00A61P15/14A61K31/722A61K31/79A61K31/047A61K31/19
Inventor 史义林陈文路倪志刚
Owner 史义林
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