Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Yang recuperating decoction soft capsule preparing method

A soft capsule and yang-tonifying technology, which is applied in capsule delivery, medical preparations containing active ingredients, and pharmaceutical formulas, can solve problems such as imperfect quality standards, poor curative effect, and inconsistent production processes, so as to improve appearance quality, Reduced packaging cost and easy portability

Inactive Publication Date: 2011-06-15
HEILONGJIANG UNIV
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the early 1980s in my country, the Beijing Great Wall Pharmaceutical Factory improved the prescription of Buyang Huanwu Decoction (60g of Astragalus, 6g of Angelica, 6g of Radix Dilong, 3g of Chuanxiong, 3g of Peach Kernel, 3g of Safflower), and developed "Xiaoshuan Oral Liquid-Buyang Huanwu Oral Liquid” has attracted widespread clinical attention, and more than 20 companies across the country are scrambling to produce it. However, due to inconsistent production processes and imperfect quality standards, quality and clinical effects have been affected.
Due to the change to oral liquid or granule granule, a large amount of active ingredients in the original decoction were lost. Due to concentration and improvement of clarity, alcohol precipitation and filtration processes were added in the process, which caused the loss of active ingredients, especially for Angelica sinensis , safflower, red peony and other medicinal materials have aromatic and resuscitating effects, and the volatile oils that have the effect of promoting blood circulation and removing stasis are difficult to retain, so it directly affects the curative effect
This is also the fundamental reason why the efficacy of the new formulation of Buyang Huanwu Decoction is inferior to that of the original decoction.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] A preparation method of Buyang Huanwu Decoction soft capsule, which comprises: firstly, 120 grams of raw astragalus, 6 grams of angelica tail, 4.5 grams of red peony, 3 grams of earthworm, 3 grams of Chuanxiong, 3 grams of peach kernel, and 3 grams of safflower , remove the mud and wash it, put it into a multifunctional traditional Chinese medicine extraction tank, add water to decoct three times, the first time is 1 hour, the second time and the third time are 1.5 hours respectively; at the same time, collect volatile oil and combine water decoction to extract Liquid, centrifugal filtration; Concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.05, then spray-dry it to become a dry extract powder and pulverize it so that the fineness is less than 120 mesh; Dissolve the extracted volatile oil in a certain amount In the edible oil, the dry extract powder is mixed with the edible oil that dissolves the extracted volatile oil, the dry extract po...

Embodiment 2

[0056] The preparation method of Buyang Huanwu Decoction soft capsule described in embodiment 1, it comprises: first raw Radix Astragali 120 grams, Dangguiwei 6 grams, Radix Paeoniae Rubra 4.5 grams, Dilong 3 grams, Rhizoma Chuanxiong 3 grams, peach kernel 3 grams, red Take 3 grams of flowers to remove the mud and wash them, put them into a multi-functional traditional Chinese medicine extraction tank, add water and decoct three times, the first time is 2 hours, the second time and the third time are 1 hour respectively; at the same time, collect volatile oil, combine water and decoct Liquid extract, centrifugal filtration; Concentrate the filtrate under reduced pressure at 80°C to a relative density of 1.10, then spray dry it into a dry extract powder and pulverize it so that the fineness is less than 120 mesh; Dissolve the extracted volatile oil in In a certain amount of edible oil, the dry extract powder is mixed with the edible oil that dissolves the extracted volatile oil,...

Embodiment 3

[0058] Embodiment 1 or 2 The preparation method of Buyang Huanwu Decoction Soft Capsules, which comprises: firstly give birth to 120 grams of Radix Astragali, 6 grams of Dangguiwei, 4.5 grams of Radix Paeoniae Rubra, 3 grams of Earthworm, 3 grams of Rhizoma Chuanxiong, 3 grams of peach kernel, safflower 3 grams, remove the mud and wash it, put it into a multi-functional traditional Chinese medicine extraction tank, add water and decoct three times, the first time is 1.5 hours, the second time and the third time are 1 hour respectively; at the same time, collect the volatile oil, combine water and decoct Liquid extract, centrifugal filtration; Concentrate the filtrate under reduced pressure at 70°C to a relative density of 1.05, then spray dry it into a dry extract powder and pulverize it so that the fineness is less than 120 mesh; Dissolve the extracted volatile oil in In a certain amount of edible oil, the dry extract powder is mixed with the edible oil that dissolves the extr...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparing method of yang-tonifying back five soup soft capsule, which comprises the following steps: putting astragalus root, chiretta rear, red peony root, sleeper, Ligusticum wallichii, peach kernel and safflower into traditional medicine extracting tank; adding into water; boiling for three times; collecting benzine; merging water boiling liquor extract; centrifuging;filtering; decompressing for filter liquor; condensing; spray-drying; grinding to 120 order; dissolving the benzine into edible oil; mixing with dried concreting powder; counting 30-40% of oil group quality in soft capsule with the dried concreting powder; grinding the mixture with colloid grinding isotrope; adding into dope of brown pigment as capsule material; producing capsule core concrete oil host liquid; stirring; fluid-pressing the capsule core concrete oil host; drying; washing ball; drying; getting the product. This product can be used to replace yang-tonifying back five soup.

Description

Technical field: [0001] The invention relates to a preparation method of making Buyang Huanwu Decoction into soft capsules. Background technique: [0002] Stroke is a general term for cerebrovascular diseases in traditional Chinese medicine, including cerebral hemorrhage and cerebral infarction. The morbidity, mortality and disability rate of stroke are quite high, and it is a kind of disease that seriously endangers human health. In my country, its incidence rate is 185-219 cases per 100,000 population per year. The incidence rate increases with age, and about 72% of first-time strokes occur in people over 65 years old. The prevalence rate is about 429-620 cases per 100,000 population. The prevention and treatment of stroke has attracted international attention, especially for the rehabilitation of stroke patients. At present, there is no very effective medicine and treatment method. Traditional Chinese medicine in our country has a long history of treating stroke and h...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/232A61K36/286A61K36/236A61K9/48A61K35/64A61P9/10A61K36/73A61K36/71A61K36/481A61K35/62
Inventor 邹积宏刘红梅邹积先
Owner HEILONGJIANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products