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Medicine composition containing sodium hyaluronate and zinc salt

A technology of sodium hyaluronate and composition, which is applied in the field of medicine and health care products, and can solve problems such as unfavorable gastric protection, unfavorable zinc function, complicated process, etc.

Active Publication Date: 2007-08-29
INST OF BIOPHARM OF SHANDONG PROVINCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation of zinc hyaluronate requires processes such as hyaluronic acid dissolution, pH adjustment, zinc salt replacement, precipitation, purification, and drying. The molecular weight is significantly reduced, and its viscosity is also significantly reduced, which is not conducive to the protection of the stomach. In addition, hyaluronic acid is a high-molecular mucopolysaccharide compound, and the content of zinc in the whole molecule is relatively low. Zinc and hyaluronic acid are in a complex state. Facilitate the function of zinc

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1: the granule of composition of the present invention

[0013] Sodium hyaluronate 200g, zinc sulfate 100g, sucrose 1500g, dextrin 1190g, low-substituted hydroxypropyl methylcellulose 10g, made into 1000 bags.

example 2

[0014] Example 2: Granules of Compositions of the Invention

[0015] Sodium hyaluronate 150g, zinc gluconate 200g, sucrose 1500g, dextrin 1140g, low-substituted hydroxypropyl methylcellulose 10g, made into 1000 bags.

Embodiment 3

[0016] Example 3: Liquid Formulations of Compositions of the Invention

[0017] Sodium hyaluronate 150g, zinc gluconate 250g, glycyrrhizin 40g, made into 20000ml, subpackaged into 1000 bottles, sterilized, to get final product.

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PUM

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Abstract

The present invention provides a medicine composition for effectively curing the diseases of gastritis, gastric ulcer and duodenal ulcer. Said medicine composition contains sodium hyaluronate, zinc salt and conventional medicinal auxiliary material.

Description

technical field [0001] The invention relates to the fields of medicine and health products, in particular to a pharmaceutical composition for treating gastritis, gastric ulcer and duodenal ulcer. The main components of the pharmaceutical composition are sodium hyaluronate and zinc salt, and the basic composition is sodium hyaluronate, zinc salt and conventional pharmaceutical auxiliary materials. The medicinal composition can give full play to the synergistic effect of sodium hyaluronate and zinc salt in treating gastritis, gastric ulcer and duodenal ulcer, and has better anti-ulcer effect. technical background [0002] Peptic ulcer is a common gastrointestinal disease that is prone to recurrence and difficult to cure. The pathogenesis is relatively complicated. Caused by the imbalance between the two factors, when the damage factors are enhanced and (or) the protective factors are weakened, ulcers can appear, which is the basic principle of ulcers. There are many reasons ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61K31/728A61K9/16A61K9/20A61K9/48A61P1/04A61K31/19
Inventor 郭学平凌沛学栾贻宏
Owner INST OF BIOPHARM OF SHANDONG PROVINCE
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