Angiitis granule and its preparation method

A technology of granules and vasculitis, which is applied in the field of traditional Chinese medicine granules and its preparation, can solve the problems of high amputation rate, no cure, and uncertain long-term curative effect, so as to promote tissue repair and regeneration, dilate blood vessels, The effect of increasing blood supply and oxygen supply to limbs

Inactive Publication Date: 2010-12-08
李丰举
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, the more effective treatment is still a comprehensive treatment based on surgical treatment, mainly including lumbar sympathetic ganglionectomy, arterial bypass grafting, venous arterialization, omentum transplantation and other treatment methods. The short-term curative effect of surgical treatment is compared Good, but the long-term curative effect is uncertain, let alone cure, and the amputation rate is still high

Method used

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  • Angiitis granule and its preparation method
  • Angiitis granule and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] A vasculitis granule, which comprises the following components: salvia miltiorrhiza, angelica, scrophulariaceae, honeysuckle, and astragalus, and the weight ratio is: salvia miltiorrhiza accounting for 25%, angelica accounting for 12%, scrophulariaceae accounting for 11%, honeysuckle Accounted for 10%, Astragalus accounted for 42%.

[0010] The preparation method is as follows: (1) adding 8 times of 80% ethanol to extract by heating and refluxing for 55 minutes, adding 6 times of 80% ethanol to the rest and extracting by heating and refluxing for 25 minutes, combining the extracts, filtering and concentrating to density 1.20 (60-75 ℃) clear ointment, set aside; (2) mix angelica, scrophulariae, honeysuckle, and astragalus, add 9 times water and fry for 65 minutes, separate the decoction and add the remaining part to 7 times water and fry for 35 minutes , combine the decoctions and filter, concentrate to a clear paste with a density of 1.12 (60-75°C), let it cool to room ...

Embodiment 2

[0012] A vasculitis granule, which comprises the following components: salvia miltiorrhiza, angelica, scrophulariaceae, honeysuckle, and astragalus, and its weight ratio is: salvia miltiorrhiza accounting for 30%, angelica accounting for 11%, scrophulariaceae accounting for 10%, honeysuckle Accounted for 11%, Astragalus accounted for 38%.

[0013] The preparation method is as follows: (1) adding 10 times of 80% ethanol to heat reflux for extracting for 65 minutes, adding 8 times of 80% ethanol to heat and reflux for extraction for 35 minutes. It is 1.22 (60-75 ℃) clear paste, set aside; (2) Angelica, scrophulariae, honeysuckle, and astragalus are mixed and then added to 7 times of water and decocted for 55 minutes. After separating the decoction, add the remaining part to 5 times of water and decoct for 25 minutes , combine the decoctions and filter, concentrate to a clear paste with a density of 1.10 (60-75°C), let it cool to room temperature, add ethanol to make the alcohol ...

Embodiment 3

[0015] A vasculitis granule, which comprises the following components: salvia miltiorrhiza, angelica, scrophulariaceae, honeysuckle, and astragalus, and the weight ratio is: salvia miltiorrhiza accounting for 28%, angelica accounting for 10%, scrophulariaceae accounting for 8%, honeysuckle Accounted for 15%, Astragalus accounted for 39%.

[0016] The preparation method is as follows: (1) adding 9 times of 80% ethanol to Plumbago Radix and extracting it under reflux for 60 minutes, adding 7 times of 80% ethanol to the remaining part and heating under reflux for 30 minutes, then combining the extracts, filtering and concentrating to a density of 1.21 (60-75 ℃) clear paste, set aside; (2) mix angelica, scrophulariae, honeysuckle, and astragalus, add 8 times of water and fry for 60 minutes, separate the decoction and add the remaining part to 6 times of water and fry for 30 minutes , combined decoctions, filtered, concentrated to a clear paste with a density of 1.11 (60-75°C), all...

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Abstract

The invention relates to a traditional medicine granule, and relative preparation, especially an angiitis granule, used to treat Buerger's disease. The invention comprises efflorescence Danshen, chiretta, scrophularia root, honeysuckle, and astragalus root. And the preparation comprises that 1, adding efflorescence Danshen into alcohol to be heated, refluxed and extracted; 2, mixing the chiretta,scrophularia root, honeysuckle, and astragalus root, to be boiled in water and concentrated into paste, to be cooled into room temperature, adding alcohol, recycling the alcohol and concentrating into paste; 3, combining two pastes, adding some dextrin and sugar to be prepared into granule to be packed. The invention can improve micro circulation, expand vessel, and accelerate the organism repairor the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine granule and a preparation method thereof, in particular to a vasculitis granule and a preparation method thereof, which are used for treating thromboangiitis obliterans. Background technique [0002] Thromboangiitis obliterans belongs to the category of “threat gangrene” in traditional Chinese medicine. It is an idiopathic, non-atherosclerotic, staged, and obstructive vascular disease. It is characterized by lower extremity pain, ulcers, and necrosis. The course of the disease is slow and difficult to treat. It often leads to severe limb dysfunction and organic damage. In severe cases, amputation is necessary, causing great pain to the patient. The exact etiology of thromboangiitis obliterans is still unknown, and the pathogenesis is complicated, so it is still inconclusive. The pathogenesis of the pathogenesis is that the blood coagulates due to cold or heat overcomes meat rot, stagnation of blo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/808A61K9/16A61P9/14
Inventor 李丰举魏开效董义臣李丰勇郭效德
Owner 李丰举
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