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A plasma substitute and its application for treating hemorrhagic shock

A technology of plasma substitutes and effects, applied in the field of plasma substitutes

Inactive Publication Date: 2007-08-01
FIELD OPERATION BLOOD TRANSFUSION INST OF PLA SCI ACAD OF MILITARY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The plasma substitutes of the current technology cannot provide the effect of improving hemorheology and reducing inflammatory injury at the same time, so it is impossible to enhance the effect of resuscitation by changing the flow state of plasma and blood formed components while volume resuscitation in hemorrhagic shock , reduce adverse reactions

Method used

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  • A plasma substitute and its application for treating hemorrhagic shock

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Embodiment Construction

[0020] The present invention aims at the deficiency of existing plasma substitutes and provides a novel plasma substitute. It can not only expand blood volume, but also improve blood rheology and microcirculation, and enhance the effect of volume resuscitation; at the same time, it can reduce the adverse reactions that may be caused by volume expansion therapy by inhibiting inflammatory damage.

[0021] The plasma substitute of the present invention can be used as a medicine for treating hemorrhagic shock. It can not only expand blood volume, but also increase the therapeutic effect of volume expansion by improving blood rheology; in addition, it can also reduce the inflammatory damage caused by shock.

[0022] The plasma substitute of the present invention is prepared by conventional volume-weight method under drug production conditions.

[0023] According to the present invention, an appropriate amount of physiologically acceptable average molecular weight is 1-400×10 3 Th...

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Abstract

The invention disclosed a kind of medicine that can treat hemorrhagic shock, especially a kind of blood plasma substitute which contains one active ingredient. The ingredient can not only expand the blood volume, it can also improve the blood rheology and relieve inflamed damage. The blood plasma substitute which has the two functions is provided in the invention. There's also provided a active ingredient which is a physically acceptable polyose high molecular compound. The active ingredient is prepared by raw plant such as astragali radix. The blood plasma substitute in the invention can be used as medicine to treat hemorrhagic shock.

Description

technical field [0001] The invention relates to a medicine used in treating hemorrhagic shock, in particular to a plasma substitute. Background technique [0002] Hemorrhagic shock (hemorrhagic shock, referred to as HS) is a common shock in which the circulating blood volume is suddenly reduced due to blood loss. A type of shock (hypovolemic shock). In hemorrhagic shock, a large amount of water, salt, plasma protein and formed blood components are seriously lost. If supplements are not given in time, the patient's life safety will be seriously threatened. [0003] Plasma substitutes can quickly restore blood volume to normal without being restricted by blood type and without the risk of transfusion-transmitted diseases. They are important drugs for rescuing and treating hemorrhagic shock and are widely used in peacetime medical care and wartime first aid. In addition to blood volume replacement, plasma substitutes can be used as a substitute for autotransfusion and hemodil...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K31/715A61P7/08
Inventor 赵莲周虹王字玲王波王广义赵雷
Owner FIELD OPERATION BLOOD TRANSFUSION INST OF PLA SCI ACAD OF MILITARY
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