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Chinese medicinal formulation for treating rheumatic and rheumatoid arthritis and preparation process thereof

A traditional Chinese medicine preparation, rheumatoid technology, applied in the directions of anti-inflammatory agents, pharmaceutical formulations, non-central analgesics, etc., can solve RA joint deformity, no obvious improvement in swelling, no rheumatoid arthritis, and insufficient drug efficacy Balanced and lasting problems, to achieve the effect of no effect on liver and kidney function, good application prospects, and reliable treatment effect

Inactive Publication Date: 2009-09-02
许博
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, glucocorticoids are generally used to treat rheumatoid arthritis, but the drug effect is not balanced and long-lasting. The application of glucocorticoids does not significantly improve the joint deformity and swelling of RA, and the toxic side effects of glucocorticoids significantly stimulate the digestive tract and affect liver and kidney functions. The impact is relatively large, and it is easy to rebound and relapse after stopping the drug
[0004] At present, although there are also reports on the treatment of rheumatoid arthritis and coronary heart disease with pangolin, there is no use of pangolin and astragalus as raw materials to treat rheumatoid arthritis.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A traditional Chinese medicine preparation for treating rheumatism and rheumatoid arthritis, prepared from 900g of pangolin and 100g of astragalus, and 2500 capsules in total. 0.40g per granule.

[0023] The preparation method of the present invention is as follows: the crude drugs of Chuanshanlong and Astragalus membranaceus are selected and weighed according to the proportion, after drying at 80°C, they are respectively crushed through a 100-mesh sieve, and then mixed evenly to form a bitter brown-yellow powder. Into the capsule, made by radiation sterilization.

Embodiment 2

[0025] A traditional Chinese medicine preparation for treating rheumatism and rheumatoid arthritis, prepared from 800g of pangolin and 120g of astragalus, and 2300 capsules in total. 0.40g per granule.

[0026] The preparation method of the present invention is as follows: the crude drugs of Chuanshanlong and Astragalus membranaceus are selected and weighed according to the proportion, after drying at 90°C, they are respectively crushed through a 150-mesh sieve, and then mixed evenly to form a bitter brown-yellow powder. Into the capsule, made by radiation sterilization.

Embodiment 3

[0028] A traditional Chinese medicine preparation for treating rheumatism and rheumatoid arthritis, prepared from 930g of pangolin and 70g of astragalus, and 2500 capsules in total. 0.40g per granule.

[0029] The preparation method of the present invention is as follows: the crude drugs of Chuanshanlong and Astragalus membranaceus are selected and weighed according to the proportion, after drying at 85°C, they are respectively crushed through a 200-mesh sieve, and then mixed evenly to form a bitter brown-yellow powder. Into the capsule, made by radiation sterilization.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating rheumatoid arthritis by using panshanlong and astragalus as raw materials and a preparation method thereof. After drying at ~90 DEG C, pulverize it through a sieve of more than 100 meshes respectively, and then mix it evenly, the brown-yellow powder with a bitter taste is put into capsules, and the finished product is obtained by radiation sterilization; the preparation is simple and convenient for patients to take, It has no toxic and side effects, obvious and reliable therapeutic effect, can be used for a long time or intermittently, and has a good application prospect.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating rheumatic and rheumatoid arthritis using pangolin and astragalus as raw materials and a preparation method thereof. Background technique: [0002] Rheumatoid arthritis (RA) is the most common inflammatory arthritis, accounting for 1% of the world's total population. The prevalence rate in our country is about 0.3%. Now that RA is an autoimmune disease, its basic pathological changes are joint synovitis, acute synovial swelling, exudation, neutrophil infiltration, synovial hyperplasia and hypertrophy, and formation of pannus. The fibrous tissue hyperplasia in the pannus invades the osteochondral tissue, causing bone tissue inflammation, necrosis, and fibrous connective tissue hyperplasia, followed by calcification, fibrous and osteoarthritis, and significant narrowing or complete disappearance of the joint cavit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K9/48A61P29/00A61P19/02
Inventor 许博刘洋博
Owner 许博
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