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Composition of medicine for treating cerebral arteriosclerosis, and preparation method

A technology for cerebral arteriosclerosis and a composition, which is applied in the field of traditional Chinese medicine, can solve the problem that the drugs for the early treatment of cerebral arteriosclerosis have not attracted the attention of pharmaceutical researchers.

Inactive Publication Date: 2008-11-12
哈尔滨儿童制药厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Among the Chinese patent medicines currently on the market, there are quite a few drugs for the treatment of cerebrovascular diseases, but most of them are mainly drugs for the treatment of acute stroke and sequelae of cerebral apoplexy. Drugs for early treatment of cerebral arteriosclerosis have not caused pharmaceutical attention of researchers

Method used

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  • Composition of medicine for treating cerebral arteriosclerosis, and preparation method
  • Composition of medicine for treating cerebral arteriosclerosis, and preparation method
  • Composition of medicine for treating cerebral arteriosclerosis, and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] [Example 1] Preparation of tablet

[0048] Take each raw material by the following parts by weight:

[0049] Prepare Polygonum multiflorum 350g, Astragalus 350g, Salvia miltiorrhiza 300g, Pueraria 300g, Ginkgo biloba 300g, Chuanxiong 300g, Alisma 300g, Gastrodia elata 250g, Uncaria 250g;

[0050] The above nine flavors should be broken into pieces as appropriate, and the Polygonum multiflorum, Danshen, Pueraria lobata, Ginkgo biloba and Alisma alisma should be prepared, heated and refluxed with 8 times the weight of 75% ethanol for 2 hours, the extract was collected, and the residue was heated and refluxed with 6 times the weight of 75% ethanol After 1.5 hours, collect the extract, combine the two extracts, filter, and decompress the filtrate to recover ethanol and concentrate to a clear paste with a relative density of about 1.10 (80°C) for later use; take Chuanxiong and add 8 times the weight of water, steam Distill to extract the volatile oil, and the collected vola...

Embodiment 2

[0051] [Example 2] Preparation of tablet

[0052] Take each raw material by the following parts by weight:

[0053] Prepare Polygonum multiflorum 350g, Astragalus 350g, Salvia miltiorrhiza 300g, Pueraria 300g, Ginkgo biloba 300g, Chuanxiong 300g, Alisma 300g, Gastrodia elata 250g, Uncaria 250g;

[0054] The above nine flavors should be crushed as appropriate, and prepared from Polygonum multiflorum, Danshen, Pueraria lobata, Ginkgo biloba and Alisma, heated and refluxed with ethanol, and the extract was collected, and the residue was heated and refluxed with ethanol, the extract was collected, and the two extracts were combined, filtered, The filtrate was decompressed to recover ethanol and concentrated into a clear ointment for later use; the volatile oil was extracted by steam distillation of Ligusticum chuanxiong, and the collected volatile oil was clathrated with β-cyclodextrin for later use; Decoct the rattan with water, combine the decoction, filter, concentrate the fil...

Embodiment 3

[0055] [embodiment 3] the preparation of capsule

[0056] Take each raw material by the following parts by weight:

[0057] Prepare Polygonum multiflorum 300g, Astragalus 300g, Salvia miltiorrhiza 250g, Pueraria 250g, Ginkgo biloba 250g, Chuanxiong 250g, Alisma 250g, Gastrodia elata 200g, Uncaria 200g;

[0058] The above nine flavors should be broken as needed, take Polygonum multiflorum, Danshen, Pueraria root, Ginkgo biloba leaves and Alisma, heat and reflux with 8 times the amount of 75% ethanol for 2 hours, collect the extract, add 6 times the amount of 75% ethanol to heat and reflux the residue After 1.5 hours, collect the extracts, combine the two extracts, filter, and recover the ethanol from the filtrate under reduced pressure and concentrate it to a clear paste with a relative density of about 1.10 (80°C) for later use; take Ligusticum chuanxiong and add 8 times the amount of water, steam Distill to extract volatile oil, collect the collected volatile oil with β-cycl...

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Abstract

A Chinese medicine in the form of tablet for treating cerebral arteriosclerosis is prepared from 9 Chinese-medicinal materials including fleece flower root, astragalus root, red sage root, pueraria root, etc. Its preparing process and quality control method are also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating cerebral arteriosclerosis prepared from Chinese herbal medicines and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Cerebrovascular disease is one of the biggest diseases that threaten the survival of human beings. In recent years, with the changes in living standards and diet structure and the reduction of physical labor in my country, the rapid aging of the population, and the sharp increase in various high-risk factors, the brain The prevalence of diseases such as arteriosclerosis, sequelae of cerebral thrombosis, and circulatory and metabolic disorders is increasing year by year, and there is a trend of younger development. Cerebral arteriosclerosis is a common and frequently-occurring disease among middle-aged and elderly people. Most of the "basic diseases" such as ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61K36/74A61K36/53A61K36/481A61K36/236A61K36/16A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P9/10
Inventor 房凯
Owner 哈尔滨儿童制药厂有限公司
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