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Multi-purpose contact lens care compositions

A contact lens, multi-purpose technology, used in glasses/protective glasses, glasses/goggles, disinfection, etc., can solve problems such as eye discomfort and eye irritation

Inactive Publication Date: 2008-06-04
ABBOTT MEDICAL OPTICS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While this composition is useful, it also presents an eye discomfort and eye irritation problem for a considerable number of people due to the need to use a borate buffer

Method used

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  • Multi-purpose contact lens care compositions
  • Multi-purpose contact lens care compositions
  • Multi-purpose contact lens care compositions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Mix the following ingredients together to make a solution:

[0048] Element Ratio [%(w / v)]

[0049] PHMB (polyhexamethylene biguanide) 1ppm

[0050] EDTA disodium salt 0.02

[0051] Poloxamer 237 [poly(oxyethylene)-poly(oxypropylene) 0.05

[0052] block copolymer]

[0053] Sodium dibasic phosphate (heptahydrate) 0.12

[0054] Monobasic sodium phosphate (monohydrate) 0.01

[0055] HPMC (Hydroxypropyl Methyl Cellulose) 0.15

[0056]Sodium chloride 0.79

[0057] Potassium chloride 0.14

[0058] Water (USP) makes up 100%

[0059] About 3 ml of the resulting solution is placed in vials containing (storage) lenses containing fatty, oily deposits, hydrophilic or soft contact lenses. The contact lenses are kept in solution at room temperature for at least about 4 hours. This treatment effectively disinfects the contact lenses. It was also found that most of the deposits previously deposited on the lenses had been removed. This indicates that the solution has ess...

Embodiment 2

[0062] The procedure of Example 1 was repeated except that the lenses were wiped and rinsed with different amounts of solution prior to placing the lenses in the vials. After at least 4 hours (in the bottle) the lenses are removed from the solution and then placed in the wearer's eye for a safe and comfortable fit.

Embodiment 3

[0064] The solution of Example 1 was used as an extended-life soak solution for hydrophilic contact lenses. Accordingly, about 3 ml of this solution is placed in a vial, and the contact lenses are soaked in this solution at room temperature for about 60 hours. After soaking, the lens is removed from the solution and placed in the wearer's eye for a safe and comfortable fit. Alternatively, remove the lens from the solution and rinse with another volume of this solution, then place the rinsed lens in the wearer's eye for safe and comfortable fit.

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PUM

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Abstract

Multi-purpose solutions for contact lens care provide substantial lens wearer / user comfort and / or acceptability. Such solutions include an aqueous liquid medium; an antimicrobial component, preferably a biguanide polymer present in an amount of less than about 5 ppm; a surfactant component, preferably a poly(oxyethylene)-poly(oxypropylene) block copolymer surfactant, in an effective amount; a phosphate buffer component in an effective amount; a viscosity inducing component, preferably selected from cellulosic derivatives, in an effective amount; and a tonicity component in an effective amount. Such solutions have substantial performance, comfort and acceptability benefits, which, ultimately, lead to ocular health advantages and avoidance of problems caused by contact lens wear.

Description

Background of the invention [0001] The present invention relates to compositions for treating, eg, disinfecting, cleaning, soaking, conditioning and / or wetting contact lenses. More specifically, the present invention relates to multipurpose solutions for treating, eg, disinfecting contact lenses, removing deposits from contact lenses, soaking, conditioning and / or wetting contact lenses, and the like. It brings many comfort and well-being benefits to the user of this solution. [0002] Contact lenses require regular handling, such as disinfection, cleaning, soaking, etc., as various contaminants, microbes, and other substances from the eye and the environment can accumulate on the lenses and / or provide a lens for safe and comfortable wear. suitable conditions. Users agree that regular and consistent handling of contact lenses is important to promote eye health and avoid contact lens wear problems. If the care solution used improves the comfort and satisfaction of the lens we...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L2/18G02C13/00A61L12/14
CPCA61L12/142A61L12/141
Inventor R·格拉哈姆J·G·维希格
Owner ABBOTT MEDICAL OPTICS INC
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