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Equipment and methodologies for magnetically-assisted delivery of therapeutic agents through barriers

a technology of magnetically assisted and therapeutic agents, applied in the field of equipment and methodologies for magnetically assisted delivery of therapeutic agents through barriers, can solve the problem that conventional transportation of therapeutic agents across barriers is accomplished without the benefit of applied magnetic fields

Inactive Publication Date: 2013-08-08
WEINBERG MEDICAL PHYSICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The invention is about using magnetic particles to transport therapeutic agents across barriers, such as the cribiform plate, which separates the nasal cavity from the cranial vault. By using magnetic gradients, the MNPs can be manipulated to position, re-position, or maintain their positions. The invention also includes the use of imaging to guide the transport, and the insertion of an applicator into a body orifice to propel the MNPs across the barrier. The "technical effect" of the invention is an improved method for delivering therapeutic agents to their desired locations in the body.

Problems solved by technology

However, conventional transportation of therapeutic agents across barriers is accomplished without the benefit of applied magnetic fields.

Method used

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  • Equipment and methodologies for magnetically-assisted delivery of therapeutic agents through barriers
  • Equipment and methodologies for magnetically-assisted delivery of therapeutic agents through barriers

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Embodiment Construction

[0012]The description of specific embodiments is not intended to be limiting of the present invention. To the contrary, those skilled in the art should appreciate that there are numerous variations and equivalents that may be employed without departing from the scope of the present invention. Those equivalents and variations are intended to be encompassed by the present invention.

[0013]In the following description of various invention embodiments, reference is made to the accompanying drawings, which form a part hereof, and in which is shown, by way of illustration, various embodiments in which the invention may be practiced. It is to be understood that other embodiments may be utilized and structural and functional modifications may be made without departing from the scope and spirit of the present invention.

[0014]Moreover, it should be understood that various connections are set forth between elements in the following description; however, these connections in general, and, unless...

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Abstract

Magnetic gradients are used to transport Magnetic Nano Particles through a barrier, for example, the cribiform (also spelled “cribriform”) plate, which is a porous bony structure which separates the nasal cavity from the cranial vault. By utilizing a configuration of magnets (whether of the electromagnetic type or permanent magnets), MNPs can be propelled, pushed, pulled or otherwise manipulated in relation to an anatomical and / or physiological barrier, to position, re-position or maintain the position(s) of the MNPs.

Description

CROSS-REFERENCE TO RELATED APPLICATION(S)[0001]This application relies for priority on United States Provisional Patent Application Ser. No. 61 / 596,395, entitled “MAGNETICALLY ASSISTED DELIVERY OF THERAPEUTIC AGENTS THROUGH BARRIERS,” filed on Feb. 8, 2012, the entirety of which being incorporated by reference herein.FIELD OF THE INVENTION[0002]Disclosed embodiments are directed, generally, to facilitate transportation of therapeutic agents across an anatomic and / or physiological barrier.DESCRIPTION OF THE RELATED ART[0003]Many scholarly works have been published concerning means for delivering therapeutic agents across an anatomic or physiological barrier. A classical approach to this endeavor is to coat the therapeutic agent with a material that is naturally transported across cells making up the barrier.SUMMARY[0004]However, conventional transportation of therapeutic agents across barriers is accomplished without the benefit of applied magnetic fields. The present invention conte...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61N2/00A61B5/01A61N2/02A61B5/055
CPCA61N2/004A61B5/055A61B5/015A61K49/1824B82Y5/00A61K47/48861A61N2/02A61K47/6923
Inventor WEINBERG, IRVING N.
Owner WEINBERG MEDICAL PHYSICS
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