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Methods and apparatus for non-invasive determination of patient's blood conditions

a technology for blood conditions and blood pressure, applied in the field of non-invasive determination of patients' blood conditions, can solve problems such as danger to the individual

Inactive Publication Date: 2011-02-10
ELFI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Both the insufficient clotting that leads to bleeding is a serious problem for some individuals, and the increased tendency to clot resulting in stroke, myocardial infarction, or deep vein thrombosis, are also dangerous to the individual.

Method used

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  • Methods and apparatus for non-invasive determination of patient's blood conditions
  • Methods and apparatus for non-invasive determination of patient's blood conditions
  • Methods and apparatus for non-invasive determination of patient's blood conditions

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Embodiment Construction

[0059]This invention is directed to in vivo methods and apparatus for determining risk of blood abnormalities, such as thrombi, in a mammal.

[0060]FIG. 1 schematically illustrates an apparatus 100 configured and operable according to the invention for use in non-invasive determination of blood-related parameters indicative of physico-chemical rheology connected property of blood, such as risk of thrombosis in a mammal. Apparatus 100 includes a measurement unit 102, a stimulus inducing device 104, and a control unit 106.

[0061]Measurement unit 102 is configured to be applied to a measurement location on a blood medium of the mammal to cause the generation of and detect optical and / or acoustic and / or electric response(s) from the measurement location. Generally, the measurement unit may be configured for carrying out at least one of the following types of measurements:

[0062]The measurement unit may carry out pure optical measurements, namely may include a source of an external electro-m...

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Abstract

A method and apparatus are presented for non-invasive determination of blood clotting related and blood circulation related parameters of a mammal. At least one stimulus ST is non-invasively induced in a blood containing medium in the mammal for a preset period of time tST. This at least one stimulus is selected to cause at least one of the following to occur: (a) inducing at least two of three Virchow's triad elements including abnormalities of blood flow; abnormalities of blood constituents and abnormalities of the blood vessel wall, and (b) inducing a change in red blood cell (RBC) aggregation or local blood viscosity. Measurements are non-invasively performed at a measurement location in the mammal by applying an external field thereto for a preset time period tm, a response of the measurement location to the applied field is detected, and measured data indicative thereof generated. At least a portion of the measured data and stimulus related data are processed so as to determine a relation between a time function of the at least one stimulus ST(t) and a time function of the measured data OR(t). This relation is indicative of at least one blood circulation and blood coagulation related parameter of the mammal.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. application Ser. No. 11 / 604,401 filed on Nov. 27, 2006 and claims priority to U.S. Application 60 / 788,074 filed on Apr. 3, 2006, all of which are incorporated by reference in their entirety.FIELD OF THE INVENTION[0002]This invention is generally in the field of non-invasive determination of patient's blood conditions, and relates to a method and apparatus for determining blood clotting and circulation related parameters.BACKGROUND OF THE INVENTION[0003]The proper control of blood clotting is essential to the health of a mammal. Both the insufficient clotting that leads to bleeding is a serious problem for some individuals, and the increased tendency to clot resulting in stroke, myocardial infarction, or deep vein thrombosis, are also dangerous to the individual.[0004]Blood coagulation is a complex defensive mechanism. Blood clotting is essential to prevent hemorrhage from damaged blood vessels. A...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K49/00A61P43/00
CPCA61B5/0048A61B5/14535A61B5/6838A61B5/1455A61B5/6826A61B5/14546A61B5/0053A61P43/00
Inventor FINE, ILYASHVARTSMAN, LEONID
Owner ELFI TECH
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