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Obesity controlling method

a controlling method and weight technology, applied in the direction of metabolism disorder, drug composition, peptide/protein ingredient, etc., can solve the problems of high invasiveness, systemic medications often display side effects, and subject patients to all the possible risks of major surgery, including infection, and achieve the effect of minimal invasiveness

Inactive Publication Date: 2010-08-12
TEMPLE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

"The present invention is a way to control obesity by injecting a material into the stomach to slow down gastric emptying. This is done in a minimally invasive way."

Problems solved by technology

In addition, it is well known that a large percentage of Americans and Europeans are considered to be obese based on height and weight ratios issued by the World Health Organization (WHO).
However, systemic medications often display side effects some of which may be severe.
Dietary changes that reduce caloric intake are also prescribed for the treatment of obesity, but such treatment requires rigorous compliance by the patient for effectiveness and is often ineffective as a result of non-compliance.
Surgical methods, however, are highly invasive and subject a patient to all the possible risks involved with major surgery including infection.

Method used

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Embodiment Construction

[0007]The entire disclosure of U.S. patent application Ser. No. 11 / 478,560 filed Jun. 29, 2006 and Ser. No. 10 / 343,668 filed Aug. 13, 2003 and U.S. Provisional Application No. 60 / 224,324 filed Aug. 11, 2000 are expressly incorporated by reference herein.

[0008]The invention is a method of treating obesity in which gastric emptying is slowed by narrowing the pyloric sphincter or pylorus. The invention comprises injecting a bio-compatible bulking material into the pyloric area of the stomach, preferably either submucosally or intramuscularly. By narrowing the pyloric region of the stomach, the stomach will fill more quickly and empty more slowly as a patient eats. The clinical effect of this treatment will be to increase the time the patient feels satiated after eating, therefore decreasing the need and desire to eat and reducing the caloric intake of the patient.

[0009]The pylorus can be caused to narrow by the injection of a bio-compatible bulking material into the mucosal or muscular...

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Abstract

A method of controlling obesity by injecting bio-compatible bulking material into the pyloric sphincter area of the stomach. The injection of this material bulks the pyloric sphincter, retarding stomach emptying and producing a feeling of satiation in the patient. The method may be supplemental and augmented by inducing flacid paralysis of the stomach by injecting botulinum toxin into the muscle tissue of the antrum or fundus of the stomach.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. patent application Ser. No. 11 / 478,560 filed Jun. 29, 2006, which is a continuation of U.S. patent application Ser. No. 10 / 343,668 filed Aug. 13, 2003, which is a National Phase Application of International Patent Application No. PCT / US01 / 24971 filed Aug. 9, 2001, which claims the benefit of U.S. Provisional Application No. 60 / 224,324 filed Aug. 11, 2000.[0002]The present invention relates to a method of controlling obesity by injecting bio-compatible bulking material into the pyloric sphincter area of the stomach. The injection of this material bulks the pyloric sphincter, retarding stomach emptying and producing a feeling of satiation in the patient.BACKGROUND OF THE INVENTION[0003]Obesity is one of the major causes of heart disease, lipid abnormalities, hypertension and osteoarthritis. Treatment of obesity has the potential to lower the risk of all of these diseases as well as improve the cond...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61M31/00A61K31/715A61K38/39
CPCA61F5/0079A61K38/39A61K31/715A61P3/04
Inventor MILLER, LARRY S.
Owner TEMPLE UNIV
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