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Biometric diagnosis

a biometric and diagnostic method technology, applied in the direction of material analysis using wave/particle radiation, radiation diagnostic techniques, instruments, etc., can solve the problems of limited test, non-invasive test for neurological and neoplastic disorders, and no completely reliable results, and achieve the effect of low cos

Inactive Publication Date: 2010-06-03
JAMES VERONICA
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Benefits of technology

[0004]The invention describes a test which provides early, low cost, totally non-invasive yet reliable tests, which could possibly be low-cost mass screening for neurological and neoplastic disorders, using samples of biological material which can be harvested at remote locations, which samples do not deteriorate with correct storage.

Problems solved by technology

There is at present no completely reliable, non-invasive test for neurological and neoplastic disorders.
Whilst specific changes in the diffraction patterns of hair have been established for breast and colon cancers and Alzheimer's disease (WO 00 / 34774), this test has complications resulting from cosmetic hair treatments such as dyes, back-combing and even brushing and by transportation through security X-rays either at airports or in the post.
In addition, many neoplastic and neurological disorders do not cause a change in the ultrastructure of hair, and therefore this test is very limited, for example prostate cancer and melanoma, even at Grade 7, do not show any changes in the structure of hair.

Method used

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Embodiment Construction

[0028]Fibre diffraction requires samples containing numerous fibres which are arranged in a regular array of parallel planes. The greater the number of planes, the better will be the final patterns obtained.

[0029]At the microscopic level, skin is comprised of three layers. Of these the dermis is the middle layer and is also the thickest of the three layers (1.5 to 4 mm thick), making up approximately 90% of the thickness of the skin. The dermis is held together by a protein called collagen which is a tough, insoluble protein found throughout the connective tissues of the body. The lower, reticular layer of the dermis is thicker and made of thick collagen fibres that are aligned parallel to the surface of the skin, making it ideal for fibre diffraction.

[0030]Anatomically fingernails and toenails are made of hard α-keratin and are produced from living skin cells in the fingers and toes as a hard, curved plate. The free edge is the part of the nail that extends past the finger or toe, ...

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Abstract

The invention provides a method of detecting neoplastic or neurological disorders comprising exposing skin or nails to X-ray diffraction and detecting changes in the ultrastructure of the skin or nails, and also provides an instrument when used in the method of detection.

Description

TECHNICAL FIELD[0001]The invention described herein relates generally to a biometric diagnostic method. In particular, the invention is directed to the use of skin or nails to detect neoplastic or neurological disorders, although the scope of the invention is not necessarily limited thereto.BACKGROUND ART[0002]There is at present no completely reliable, non-invasive test for neurological and neoplastic disorders. Whilst specific changes in the diffraction patterns of hair have been established for breast and colon cancers and Alzheimer's disease (WO 00 / 34774), this test has complications resulting from cosmetic hair treatments such as dyes, back-combing and even brushing and by transportation through security X-rays either at airports or in the post. In addition, many neoplastic and neurological disorders do not cause a change in the ultrastructure of hair, and therefore this test is very limited, for example prostate cancer and melanoma, even at Grade 7, do not show any changes in ...

Claims

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Application Information

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IPC IPC(8): G01N23/201G01N23/20
CPCA61B6/483A61B6/48G01N2223/612A61B6/508G01N23/20A61B6/4092G01N33/483
Inventor JAMES, VERONICA
Owner JAMES VERONICA
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