Devices and methods for tissue invagination

Abstract

Surgical devices and methods used for invaginating tissue during, for example, an endoscopic fundoplication procedure, are disclosed. The device includes an elongated tube having a proximal end configured to extend outside of the body and a distal end configured to extend proximate the tissue to be invaginated, and a distal member coupled to the distal end of the tube. The distal member is configured to hold or grasp the tissue to be invaginated. The devices may include a protective distal sleeve.

Description

FIELD OF THE INVENTION [0001] The present invention relates to endoscopic devices and related methods. In particular, the present invention relates to endoscopic devices and methods used in, for example, a tissue invagination procedure for treatment of Gastroesophageal Reflux Disease (GERD). BACKGROUND OF THE INVENTION [0002] Gastroesophageal reflux occurs when stomach acid enters the esophagus. This reflux of acid into the esophagus occurs naturally in healthy individuals, but also may become a pathological condition in others. Effects from gastroesophageal reflux range from mild to severe. Mild effects include heartburn, a burning sensation experienced behind the breastbone. More severe effects include a variety of complications, such as esophageal erosion, esophageal ulcers, esophageal stricture, abnormal epithelium (e.g., Barrett's esophagus), and / or pulmonary aspiration. These various clinical conditions and changes in tissue structure that result from reflux of stomach acid in...

AI Technical Summary

Benefits of technology

[0009] Therefore, it is accordingly an object of the present invention to provide less invasive devices and methods for performing the fundoplication procedure. This is achieved by using an invagination device which can be endoluminally delivered through the esophagus, thereby eliminating the need for highly invasive, physiologically insulting surgical procedures.

Problems solved by technology

This reflux of acid into the esophagus occurs naturally in healthy individuals, but also may become a pathological condition in others.

Transient relaxations of the LES 2 do occur in healthy individuals, typically resulting in occasional bouts of heartburn.

As with any surgery, the attendant risks are great.

Due to relatively large incisions necessary in the performance of open surgery, relatively large amount of blood is lost, the risk of infection increases, and the potential for post-operative hernias is high.

Further, the relatively large incisions necessary in the performance of open surgery require extended recovery times for the incision to heal.

This procedure is still relatively invasive requiring incisions through the stomach, which has a risk of infection.

The location of the incision in the abdominal wall presents a risk of other negative effects, such as sepsis, which can be caused by leakage of septic fluid contained in the stomach.

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