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Method and apparatus for modifying pressure within a fluid dispenser

a fluid dispenser and pressure technology, applied in the field of biological reaction systems, can solve the problems of limited computer control, and achieve the effects of convenient manufacturing, convenient primeing, and efficient and reliabl

Inactive Publication Date: 2005-06-23
VENTANA MEDICAL SYST INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent describes a fluid dispenser for an automated biological reaction system. The dispenser has a reservoir chamber and a dispense chamber that are connected through a pressure differential. The dispenser can transfer fluid between the chambers based on pressure differential. The patent also describes different aspects of the fluid dispenser, including a method of assembly, a method of filling and priming, a method of applying consistent amounts of fluid on a slide, a method of washing a slide, and an automated biological reaction apparatus. The technical effects of the patent are improved accuracy and efficiency in dispensing fluids for biological reactions.

Problems solved by technology

However, the computer control is limited in that it is dedicated to and resident on the biological reaction apparatus.

Method used

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  • Method and apparatus for modifying pressure within a fluid dispenser
  • Method and apparatus for modifying pressure within a fluid dispenser
  • Method and apparatus for modifying pressure within a fluid dispenser

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Embodiment Construction

[0099] The automated immunostaining system of this invention performs all steps of immunohistochemical irrespective of complexity or their order, at the time and temperature, and in the environment needed. Specially prepared slides containing a bar code identifier and a mounted tissue section are placed in special supports on a carousel, subjected to a preprogrammed sequence of reactions, and are removed from the carousel, ready for examination. For purposes of clarity of the following description of the apparatus of this invention and not by way of limitation, the apparatus will be described in terms of immunohistochemical processes.

[0100]FIG. 1 is front right isometric view of the automated biological reaction system with a host device 32 and one remote device 166. The remote device 166 includes a staining module 167, bulk fluid module 230 and the host device 32 includes a host computer 33, a monitor 34, a keyboard 35 and a mouse 37. FIG. 2 is a front right isometric view of the ...

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Abstract

A method and apparatus for an automated biological reaction system is provided. In the processing of a biological reaction system, there is a need for consistently placing an amount of fluid on a slide. In order to accomplish this, several methods are used including a consistency pulse and a volume adjust means. Moreover, in order to reliably operate an automated biological reaction system, the dispenser must be reliable, easy to assemble and accurate. Among other things, in order to accomplish this, the dispense chamber is substantially in line with the reservoir chamber, the reservoir chamber piston is removed, and the flow of fluid through the dispenser is simplified. Further, in order to operate the automated biological reaction system more reliably, the system is designed in modular pieces with higher functions performed by a host device and the execution of the staining operations performed by remote devices. Also, to reliably catalog data which is used by the automated biological reaction system, data is loaded to a memory device, which in turn is used by the operator to update the operator's databases. The generation of the sequence of steps for the automated biological reaction device based on data loaded by the operator, including checks to determine the ability to complete the run, is provided.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application is a continuation-in-part of co-pending U.S. patent application Ser. No. 10 / 060,602, filed Jan. 30, 2002. The application is also a continuation-in-part of co-pending U.S. patent application Ser. No. 09 / 896,649, filed on Jun. 29, 2001, which is a continuation of U.S. patent application Ser. No. 09 / 483,218 filed on Jan. 14, 2000, now U.S. Pat. No. 6,416,713, which is a divisional of U.S. patent application Ser. No. 08 / 995,052 filed on Dec. 19, 1997, now U.S. Pat. No. 6,045,759, which is a continuation-in-part of U.S. patent application Ser. No. 08 / 909,335 filed on Aug. 11, 1997, now U.S. Pat. No. 6,093,574. This application incorporates by reference all of the U.S. patent applications listed above in their entirety. This application also incorporates by reference U.S. Pat. Nos. 6,416,713, 6,045,759 and 6,093,574 in their entirety.NOTICE REGARDING COPYRIGHT [0002] A portion of the disclosure of this patent document contai...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G01N1/31G01N35/00G01N35/10
CPCG01N1/312G01N35/1002G01N2035/1034G01N2001/317G01N35/1016
Inventor LEMME, CHARLES D.RIZZO, VINCENT R. JR.DRUYOR-SANCHEZ, BOBBIFORD, ANTHONYHEILMAN, BRONWENMCDANIEL, DARINMCGRAW, BRIANMEAD, STEPHENRICHARDS, WILLIAMSHOWALTER, WAYNE
Owner VENTANA MEDICAL SYST INC
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