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Method and system for testing heterodyne phase of resonance biochemical multichannel of surface plasma

A surface plasmon and phase detection technology, which is applied in the field of biotechnology detection, can solve problems such as difficult to meet the requirements, and achieve the effects of short return optical path, no labeling, real-time detection, and high sensitivity

Inactive Publication Date: 2007-05-16
TSINGHUA UNIV
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Benefits of technology

This technology provides an improved way to measure changes during interactions between different substances called binding partners or receptors. By passing two types of lights with opposite phases alternately over them, there are many possible ways to make these measurements faster without causing any damage from unlabeled samples. These techniques also allow researchers to study how proteins interact within cells more accurately than before they were analyzed alone.

Problems solved by technology

Technologies described in this patents involve multiple techniques such as photoelectric conversion, fluorescent emission spectroscopy, optical coherence tomography, and Fourier transform infrared spectrometry. These technics aim to improve upon current technology used for bioimaging purposes due to their ability to accurately measure various parameters related to specific types of substances involved in complex biomechanisms.

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  • Method and system for testing heterodyne phase of resonance biochemical multichannel of surface plasma
  • Method and system for testing heterodyne phase of resonance biochemical multichannel of surface plasma
  • Method and system for testing heterodyne phase of resonance biochemical multichannel of surface plasma

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[0034] The surface plasmon resonance biochemical multi-channel heterodyne phase detection method and its system protected by the present invention will be described below in conjunction with the accompanying drawings.

[0035] The present invention is composed of four major parts, the biosensing unit 1 , the incident arm, the reflection arm and the signal processing unit 29 , as shown in FIG. 4 . Wherein, the biosensing unit 1 is a surface plasmon resonance imaging biosensor, comprising a right angle, isosceles triangle or trapezoidal prism 30, a refractive index oil layer 31 and a multi-channel sensor chip 32 placed on the bottom surface of the right angle, isosceles or trapezoidal prism 30 And the sample pool 17 placed under the multi-channel sensing chip 32; the incident arm is located on one side of the biosensing unit, and is made up of a chirped optical fiber heterodyne interferometer 64, a polarizer 24 and the first lens 25; the The chirp optical fiber heterodyne interf...

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Abstract

This invention relates to surface plasma resonance multi-channel outside phase test method and its system in biological test field, which is based on surface plasma resonance principle and adopts outside phase difference test method, wherein, the system is composed of incidence arm, biological sensor unit, reflection arm and signal process unit; the incidence arm comprises multi-channel linear modulation fiber intervene, bias slice and first lens and reflection arm. The invention is characterized by the following: light reflected by multiple channel chips is projected to reflection lens along original path through second sensor chip at same one test point.

Description

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Claims

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Application Information

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Owner TSINGHUA UNIV
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