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Application of interleukins-15 in preparation of medicine for tumor immunization therapy and immunotherapy drug

An interleukin, anti-tumor metastasis technology, applied in the field of biopharmaceuticals, can solve the problem that the anti-tumor metastasis and tumor recurrence prevention effects of rhIL-2 are not ideal, and achieve the goal of preventing tumor recurrence, inhibiting tumor growth, and prolonging survival time. Effect

Inactive Publication Date: 2010-11-10
THE INST OF BASIC MEDICAL SCI OF CHINESE ACAD OF MEDICAL SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Moreover, the inventors also found that the effect of rhIL-2 on anti-tumor metastasis and prevention of tumor recurrence is not ideal enough

Method used

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  • Application of interleukins-15 in preparation of medicine for tumor immunization therapy and immunotherapy drug
  • Application of interleukins-15 in preparation of medicine for tumor immunization therapy and immunotherapy drug
  • Application of interleukins-15 in preparation of medicine for tumor immunization therapy and immunotherapy drug

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Abstract

The invention relates to an application of recombined protein, especially the application of recombinant human interleukin-15, rhIL-15 used to prepare the tumor immunity medicine. And the invention also provides said drug.

Description

Application of recombinant human interleukin-15 in the preparation of drugs for anti-tumor metastasis and prevention of tumor recurrence and a drug for anti-tumor metastasis and prevention of tumor recurrence Technical field The invention belongs to the field of biopharmaceuticals, and specifically relates to the medical use of a recombinant protein, that is, to a medicine containing recombinant human interleukin-15 (rhIL-15) in tumor immunotherapy. The invention also relates to a pharmaceutical composition containing the recombinant protein and a specific powder for injection. Background technique Interleukin-15 (IL-15) is a cytokine with immunomodulatory activity discovered by Grabstein et al. in 1994. The mature protein consists of 114 amino acid residues and has a molecular weight of 14-15kD (GrabsteinKH, et al. CloningofaTcellgrowthfactorthatinteractswiththeβchainoftheinterleukin). -2 receptor. Science, 1994; 264: 965-68.). With the deepening of its research, people have...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/20A61P35/00A61P37/02
Inventor 何维唐峰崔莲仙沈永泉薛莉巴德年
Owner THE INST OF BASIC MEDICAL SCI OF CHINESE ACAD OF MEDICAL SCI
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