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Medicine for treating benign prostate hyperplasia and method of prepn. of the same

A benign prostatic hyperplasia technology, used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as difficulty in urination, urethral extrusion, etc., achieve high bioavailability, reduce wet and dry weights , the effect of alleviating symptoms of dysuria

Inactive Publication Date: 2007-03-07
ZHEJIANG CONBA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Difficulty urinating due to increased prostate tissue that presses against the urethra

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Preparation of capsules

[0060] Weigh according to the prescription: 300g astragalus, 180g peach kernel, 180g zedoary, 20g rhubarb, 240g smilax, 400g coix seed, 300g motherwort, 300g prunella vulgaris, 120g cinnamon, 180g bellflower, 180g bean root, and 180g achyranthes bidentata.

[0061] Take cinnamon, rhubarb, coix seed (50% or 200g), and peach kernel (5% or 9g), mix and grind them into fine powder; extract the volatile oil from Curcuma with steam distillation for 8 hours, put the aqueous solution in a container for later use, and keep the medicinal residue. Take the volatile oil and use 6 times the amount of β-cyclodextrin to get inclusions; decoct and extract Astragalus three times, adding 8 times water each time, decocting for 1.5 hours, combining three decoctions, filtering, and concentrating until the relative density is 1.05-1.35 (measured at 70°C), take it out, let it cool, add ethanol to make the ethanol content reach 60%, leave it for 24 hours, filter, and ...

Embodiment 2

[0063] Weigh according to the prescription: Astragalus 310g, peach kernel 200g, curcuma 190g, rhubarb 20g, Smilax 250g, coix seed 400g, motherwort 310g, Prunella vulgaris 300g, bellflower 152g, cinnamon 0g, bean root 258g, Sichuan achyranthes bidentata 190g.

[0064] Take cinnamon, rhubarb, coix seed 50% (ie 200g), and peach kernel 5% (ie 10g) and mix and grind into fine powder; Zedoary decoction pieces are steam-distilled to extract volatile oil for 6 hours, put the aqueous solution in a container for later use, and keep the drug residue. Take the volatile oil, and use 5 times the amount of β-cyclodextrin to get inclusions; decoct and extract Astragalus three times, add 6 times of water each time, decoct for 1 hour, combine three decoctions, filter, and concentrate to a relative density of 1.05-1.35 (measured at 70°C), take it out, let it cool, add ethanol to make the ethanol content reach 40%, leave it for 18 hours, filter, and get ethanol liquid; the remaining peach kernel 1...

Embodiment 3

[0066] Tablet preparation

[0067] Weigh according to the prescription: 516g of astragalus, 51.6g of peach kernel, 258g of curcuma, 0g of rhubarb, 77.4g of Smilax tuckahoe, 619.2g of coix seed, 129g of motherwort, 516g of Prunella vulgaris, 206.4g of cinnamon, 77.4g of bellflower, 51.6g of bean root, Sichuan Achyranthes bidentata 77.4g.

[0068] Take cinnamon, rhubarb, coix seed 61.92g, and peach kernel 15.48g, mix and grind into fine powder; Zedoary decoction pieces are steam-distilled to extract volatile oil for 8 hours, put the aqueous solution in a container for later use, and keep the drug residue. Take the volatile oil, and use 7 times the amount of β-cyclodextrin to get inclusions; Astragalus is decocted and extracted three times, adding 10 times of water each time, decocting for 3 hours, combining three decoctions, filtering, and concentrating until the relative density is 1.05-1.35 (measured at 70°C), take it out, let it cool, add ethanol to make the ethanol content ...

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Abstract

The invention relates to a medicinal preparation for treating benign prostate hyperplasia and process for its preparation, wherein the medicament is prepared from astragalus root, peach kernels, zedoary, rhubarb horsetails, poria cocos, coix seed, motherwort, selfheal, Cinnamomum cassia, root of ballon flower, subprostrate sophora root, achyranthes and cyathula root, and medicinal auxiliary materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation and a preparation method thereof, in particular to a medicine for treating benign prostatic hyperplasia and a preparation method thereof. The name of the medicine is Huang'e Tongguan Capsule. Background technique [0002] The prostate gland is made up of glands and muscles that grow with age. Their overgrowth can cause benign prostatic hyperplasia. Difficulty urinating due to the increase in prostate tissue, causing compression on the urethra. As the pace of life continues to accelerate, the number of patients with benign prostatic hyperplasia is increasing day by day. According to data, patients with benign prostatic hyperplasia tend to be younger. BPH is not cancer, nor can it turn into cancer; these benign growths of the prostate gland are slow and do not spread to other parts of the body. However, the two diseases may coexist at the same time...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P13/08
Inventor 贾金铭
Owner ZHEJIANG CONBA PHARMA
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