Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

NK-1 receptor antagonists for improving anesthesia recovery

A receptor antagonist, salt-accepting technology, used in the field of improving anesthesia recovery, can solve the problem of harming oneself and medical staff

Inactive Publication Date: 2007-02-14
PFIZER PROD INC
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The risk of this type of injury is very high in horses, who often injure themselves and medical staff as they recover from anesthesia, despite dedicated recovery stables

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • NK-1 receptor antagonists for improving anesthesia recovery
  • NK-1 receptor antagonists for improving anesthesia recovery
  • NK-1 receptor antagonists for improving anesthesia recovery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] The present invention provides a method of improving recovery from anesthesia in a patient by administering an NK-1 antagonist before, during or after administration of general anesthesia. In particular, the present invention relates to the administration of a compound of formula I or Ia before, during or after administration of general anesthesia to improve recovery from anesthesia in a patient. If the compound of formula I or Ia is administered after general anesthesia, it is preferably administered within about 30 minutes of the recovery period.

[0033] Compounds of formula I and Ia can be prepared as described in US Patent No. 6,222,038 or US Patent No. 6,255,038. Salts of compounds of formula I or Ia, in particular citrate salts, can be prepared as described in the aforementioned patents. Alternatively, compounds of formula I may also be prepared as described in co-pending US Provisional Patent Application Serial No. 60 / 541,323, assigned to and owned by Pfizer, I...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention is directed to the administration of a compound of the Formula (I)and (Ia), wherein R<2> is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl, to an animal to improve anesthesia recovery.

Description

technical field [0001] The present invention relates to a method for improving recovery from anesthesia, which comprises administering an NK-1 receptor antagonist pharmaceutical composition in a therapeutically effective amount to animals. [0002] In particular, the present invention relates to administering to animals a compound of formula I to improve recovery from anesthesia, wherein R 2 selected from methyl, ethyl, isopropyl, sec-butyl and tert-butyl. [0003] [0004] In particular, the present invention relates to administering compounds of formula Ia to animals to improve recovery from anesthesia. [0005] Background technique [0006] Compounds of Formula I and Ia, NK-1 receptor antagonists, are effective antiemetics in mammals. Compounds of formula I and Ia are the subject of US Patent Nos. 6,222,038 and 6,255,320. The preparation of the compounds is described therein. US Patent No. 5,393,762 also describes pharmaceutical compositions of NK-1 receptor ant...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/439A61P39/00A61P41/00
CPCA61K31/00A61K47/26B82Y5/00A61K31/439A61K47/48969A61K31/4745A61K9/0019A61K47/6951A61P23/00A61P25/00A61P25/14A61P39/00A61P41/00A61P43/00
Inventor M·A·希克曼C·E·米斯克尔
Owner PFIZER PROD INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com