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Application of spanishneedles herb flavonid in preparing medicine for preventing and treating liver fibrosis

A technology of liver fibrosis and total flavonoids, applied in the field of application of total flavonoids of ghost needles in the prevention and treatment of liver fibrosis

Active Publication Date: 2007-01-03
ANHUI MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These are all drugs used to prevent and treat cardiovascular and cerebrovascular diseases such as hypertension, and the development of this drug for liver fibrosis has not yet been completed.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116] Weigh 10kg of the crude drug of Acanthopanax, crush it, add 100L of 80% ethanol, heat reflux extraction twice, each time for 1h, combine the extracts, recover the ethanol, and concentrate under reduced pressure to obtain the extract. The extract is dissolved in water, left to stand, filtered, and the clarified liquid is put on a macroporous resin column, and the eluted part with 80% ethanol is collected after washing with water. The ethanol is recovered, concentrated under reduced pressure, and dried to obtain the extract, which is the total flavonoids of P. The total flavonoids of the ghost needle grass is a yellow-green powder with an aromatic taste and is easy to deliquescence; the total flavonoid content of its main components is 20-60%. The extract can be added with corresponding auxiliary materials to make tablets, capsules, sustained-release tablets, dropping pills, granules, and granules, and further purified to make injections.

[0117] The clinical recommende...

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PUM

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Abstract

The present invention relates to the use of sponish needles herb flavonid, and is especially application of sponish needles herb flavonid in preparing medicine for preventing and treating liver fibrosis. Sponish needles herb flavonid is the effective part extracted from sponish needles herb. Animal experiments show that sponish needles herb flavonid can protect mouse from acute liver damage caused by carbon tetrachloride and can prevent and treat chronic liver fibrosis of rat caused by carbon tetrachloride and pig's serum. Therefore, sponish needles herb flavonid may be used in preparing medicine for preventing and treating liver fibrosis.

Description

technical field [0001] The present invention relates to the application of the total flavonoids of ghost needles, specifically the application of the total flavonoids of ghost needles in medicines for preventing and treating liver fibrosis. Background technique [0002] Ghost needle grass is also known as mother-in-law needle, ghost branch grass, little ghost needle, sticky grass, etc. Its medicinal use has a long history and was first recorded in Tang. It is non-poisonous. It is mainly bitten by snakes and spiders. It is crushed with a pestle and sprinkled with a pestle. It is also taken with a pestle and twisted juice. There are twigs and square stems on the side of the raw land. The whole herb can be used as a medicinal herb. It tastes bitter and non-toxic. It has the functions of clearing away heat and detoxification, dispelling blood stasis and reducing swelling. Pain, bruises, snake bites, etc. In order to better understand and understand this natural resource, and b...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61P1/16
Inventor 陈飞虎李俊袁丽萍
Owner ANHUI MEDICAL UNIV
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