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Postpartum laonurus medicinal preparation and its new preparation method

A preparation, motherwort technology, applied in the direction of pill delivery, pharmaceutical formula, aerosol delivery, etc., can solve the problems of large dosage, many impurities, and affecting clinical application

Inactive Publication Date: 2006-08-30
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] The preparation method of dropping pill of the present invention:

[0067] prescription:

[0068] Motherwort 240g Angelica 60g Chuanxiong 60g

[0069] Radix Paeoniae Rubra (stir-fried) 60g Rhizoma Cyperi (roasted with vinegar) 60g Corydalis Corydalis (roasted with vinegar) 60g

[0070] Rehmannia glutinosa 60g Safflower 75g Peach kernel (stir-fried) 75g

[0071] PEG4000 100g

[0072] Makes 1000 pills

[0073] Preparation:

[0074] (1) Take angelica, chuanxiong, and Cyperus cyperus, and use supercritical extraction method (or steam distillation method): put it into a supercritical extraction tank, under the conditions of pressure 20MPa, temperature 40°C, and flow rate 20L / h Extraction under low temperature for 3.0h; analyze with pressure of 5.5MPa, temperature of 34.5°C (separation I), 34.8°C (separation II) to obtain the extract; β-CD inclusion, the best process is: β-CD to water ratio The ratio of oil to β-CD is 1:8, the ratio of oil to β-CD is 1:5, and ultrasonic...

Embodiment 2

[0079] The preparation method of soft capsule of the present invention:

[0080] prescription:

[0081] Motherwort 1392g Angelica 348g Chuanxiong 348g

[0082] Radix Paeoniae Rubra (Stir-fried) 348g Cyperi Cyperi (Stir-fried with Vinegar) 348g Corydalis Corydalis (Stir-fried with Vinegar) 348g

[0083] Rehmannia glutinosa 348g Safflower 435g Peach kernel (stir-fried) 435g

[0084] PEG400600g

[0085] Makes 1000 capsules

[0086] Preparation:

[0087] (1) Take angelica, chuanxiong, and Cyperus cyperus, and use supercritical extraction method (or steam distillation method): put it into a supercritical extraction tank, under the conditions of pressure 20MPa, temperature 40°C, and flow rate 20L / h Extraction under low temperature for 3.0h; analyze with pressure of 5.5MPa, temperature of 34.5°C (separation I), 34.8°C (separation II) to obtain the extract; β-CD inclusion, the best process is: β-CD to water ratio The ratio of oil to β-CD is 1:8, the ratio of oil to β-CD is 1:5, ...

Embodiment 3

[0092] The preparation method of granule of the present invention:

[0093] prescription:

[0094] Motherwort 720g Angelica 180g Chuanxiong 180g

[0095] Radix Paeoniae Rubra (stir-fried) 180g Rhizoma Cyperi (stir-fried with vinegar) 180g Corydalis Corydalis (stir-fried with vinegar) 180g

[0096] Rehmannia glutinosa 180g Safflower 225g Peach kernel (stir-fried) 225g

[0097] Made into 1000g

[0098] Preparation:

[0099] (1) Take angelica, chuanxiong and cyperus into powder and use them as medicine;

[0100] (2) Take motherwort, add water and decoct 3 times, 1 hour each time, combine the decoction, filter, the filtrate is concentrated to a certain volume, mix with 8 times the amount of 95% ethanol, let stand, filter, and concentrate the filtrate under reduced pressure into a thick extract, set aside;

[0101] (3) Get the remaining medical materials, according to the percolation method (appendix 10) under the liquid extract and extract item, carry out percolation after s...

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PUM

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Abstract

A composite Chinese medicine in the form of dripping pill and soft capsule for treating puerperal lochiorrhagia, abdominalgia and menalgia, and its preparing process are disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription and a preparation process thereof for postpartum incessant lochia, abdominal pain due to blood stasis and dysmenorrhea due to blood stasis. Background technique: [0002] Postpartum lochia, abdominal pain due to blood stasis, and dysmenorrhea due to blood stasis are common clinical symptoms. Traditional Chinese medicine often adopts methods of promoting blood circulation to remove blood stasis, regulating qi and relieving pain to treat them, and the curative effect is remarkable. Postpartum Yimu Pill is its representative medicine. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the presen...

Claims

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Application Information

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IPC IPC(8): A61K36/89A61K9/06A61K9/16A61K9/20A61K9/48A61P15/00
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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