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Application wogonin for preparing medicine to treat leukaemia

A technology of wogonin and leukemia, which is applied in the field of application of wogonin in the preparation of medicines for treating leukemia, and achieves the effect of being beneficial to clinical application and having little toxic effect

Active Publication Date: 2006-06-14
CHINA PHARM UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, the application of wogonin in the preparation of drugs for the treatment of leukemia, especially the research on the preparation of wogonin in the preparation of drugs for inducing the directed differentiation of leukemia cells, has not been reported yet.

Method used

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  • Application wogonin for preparing medicine to treat leukaemia
  • Application wogonin for preparing medicine to treat leukaemia
  • Application wogonin for preparing medicine to treat leukaemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Take 10g of wogonin, add appropriate auxiliary materials for injections (including freeze-dried powder injections and sterile subpackaged dry powder injections), and prepare anti-leukemia drug injections according to the injection (including freeze-dried powder injections and sterile subpackaged dry powder injections) process.

Embodiment 2

[0068] Take wogonin 10g, add suitable auxiliary materials for tablets (including sustained and controlled release tablets, matrix tablets, coated tablets, dispersible tablets, etc.), press the tablet (including sustained and controlled release tablets, matrix tablets, coated tablets, dispersible tablets, etc.) ) technology is prepared into anti-leukemia tablet.

Embodiment 3

[0070] Take 10 g of wogonin, add appropriate auxiliary materials for capsules, and prepare anti-leukemia drug capsules according to the capsule process.

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PUM

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Abstract

An application of wogonin in preparing the medicines for treating particular-type leukemia by inducing the differentiation of leukemia cells to particle system is disclosed.

Description

technical field [0001] The invention belongs to the field of pharmacy and relates to the application of wogonin in the preparation of medicines for treating leukemia. Background technique [0002] Leukemia is a malignant disease that originates from the hematopoietic system and is characterized by the production and accumulation of a large number of immature and abnormal white blood cells in the bone marrow or other hematopoietic tissues. From the perspective of form, most leukemia cells are immature and abnormally morphological white blood cells; in terms of function, leukemia cells have the same characteristics as tumor cells: leukemia cells proliferate in a tumorous manner, which cannot be controlled, often leading to the inhibition and failure of bone marrow hematopoietic function. It can cause anemia, neutropenia and thrombocytopenia in patients. Leukemic cells can infiltrate various tissues and organs throughout the body, and damage the functions of various organs, suc...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61P35/00
Inventor 郭青龙张坤俞军尤启冬王伟张海伟顾红燕赵丽胡扬
Owner CHINA PHARM UNIV
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