Dispersion tablet of small-thorn hedgehog hydnum and preparing method
A small hedgehog and dispersible tablet technology, which is applied in the digestive system, pill delivery, drug combination, etc., can solve the problems of diabetics who cannot take it, the phenomenon of particle moisture absorption, and large packaging volume, and achieves simple manufacturing methods and bioavailability The effect of high degree and small oral dose
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Embodiment 1
[0024] Calculated by preparing 1000 dispersible tablets of Hericium erinaceus, get Hericium erinaceus fermented extract 72g, starch 21g, microcrystalline cellulose 76g, cross-linked polyvinylpyrrolidone 9g, sodium carboxymethyl starch 9g, 30% ethanol 65ml, micronized silica gel 1g, magnesium stearate 1g.
[0025] Preparation Process
[0026] (1) Take starch, microcrystalline cellulose, and sodium carboxymethyl starch according to the prescription, place them at 80°C, dry them for 4 hours, and pass through a 100-mesh sieve.
[0027] (2) According to the prescription, take the Hericium erinaceus fermented extract and fully mix it with (1) dried auxiliary materials to make a soft material, granulate with a 24-mesh sieve, dry at 55°C, and granulate with a 20-mesh sieve.
[0028] (3) Take the granules of (2) and mix them well with a lubricant, compress into tablets, submit for inspection, pack, and obtain dispersible tablets.
[0029] Inspection: Take 2 dispersible tablets for un...
Embodiment 2
[0039] Calculated by preparing 1000 dispersible tablets of Hericium erinaceus, get Hericium erinaceus fermented extract 144g, starch 52g, microcrystalline cellulose 160g, cross-linked polyvinylpyrrolidone 20g, sodium carboxymethyl starch 20g, ethyl cellulose Su 115g, micronized silica gel 2g, talcum powder 2g.
[0040] Preparation process, dispersion check, assay is the same as [Example 1]
Embodiment 3
[0042] Calculated by preparing 1000 dispersible tablets of Hericium erinaceus, get Hericium erinaceus fermented extract 152g, starch 44g, microcrystalline cellulose 160g, cross-linked polyvinylpyrrolidone 20g, sodium carboxymethyl starch 20g, carboxymethyl starch Sodium cellulose 130g, micronized silica gel 2g, magnesium stearate 2g.
[0043] Preparation process, dispersion check, assay is the same as [Example 1]
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