Antituberculosis pharmaceutical composition

Abstract

The invention relates to an antituberculosis drug combination, prepared of rifampicin, isonicotinyl hydrazine, pyrazinamide, ethambutol hydrochloride and other auxiliaries, able to effectively overcome problems of drug resistance, improving compliance of patient, etc. It is applied in a compound form, which can avoid curing by single antituberculosis drug, thus avoiding selective drug resistance caused by single drug; the patients are willing to accept this, avoiding irregular drug application caused by simultaneously taking several drugs and different numbers of drug tablets, or taking more or less drugs.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to an anti-tuberculosis pharmaceutical composition. Background technique [0002] Tuberculosis is a chronic infectious disease. Unlike smallpox or polio, there is no guarantee that you will never get tuberculosis if you get vaccinated. According to information, in recent years, due to the relaxation of people's vigilance against tuberculosis, a large increase in poverty and floating population, as well as the emergence of drug-resistant strains and AIDS, tuberculosis has experienced a big rebound all over the world. The World Health Organization reports that tuberculosis is still the first killer of infectious diseases. About one-third (about 2 billion) people in the world are infected with tuberculosis. Among the existing 20 million tuberculosis patients, 95% are in developing countries. There are about 9 million new patients in the world every year, and 75...

AI Technical Summary

Problems solved by technology

[0003] At present, most of the drugs used for tuberculosis are single drugs, and the anti-tuberculosis treatment takes a long time. Not only can tuberculosis bacteria not be killed, but also drug-resistant strains will be produced; and during routine treatment, patients must take corrected and sufficient anti-tuberculosis drugs , it is easy to cause side effects in patients with light weight due to high dose, and it is difficult for patients with high body weight to obtain ideal treatment

In addition, because the number of drugs taken at the same time is large, the patient's compliance is not good, and it is easy to cause wrong doses, missed doses and other behaviors that are not conducive to treatment.