Medicinal polysaccharide component of spinulate hedgehog fungus, its prepn and medicinal composition
A technology of Hericium erinaceus and polysaccharides, which can be used in drug combinations, organic active ingredients, and pharmaceutical formulas, and can solve problems such as unclear active substance ingredients, inconvenient application for diabetics, and limitations in therapeutic applications.
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Embodiment 1
[0070] Weigh 1Kg of the fruiting body of Hericium erinaceus, add 20Kg of water, and extract 3 times at 95°C for 1 hour each time. The extracts were combined, filtered, concentrated in vacuo under reduced pressure, and the thermal specific gravity was 1.04, and finely filtered. Add edible ethanol to precipitate, and the final concentration reaches 70%. Filter to collect the precipitate and dissolve in water. Centrifuge to remove slag, take the supernatant alcohol precipitation (alcohol concentration 70%) 2-3 times, and collect the precipitate-polysaccharide (HP) 70g.
Embodiment 2
[0072] Weigh 1Kg of Hericium erinaceus mycelium, add 20Kg of water, and extract at 98°C for 3 times, each time for 1 hour. The extracts were combined, filtered, concentrated in vacuo under reduced pressure, and the thermal specific gravity was 1.04, and finely filtered. Add edible ethanol to precipitate, and the final concentration reaches 80%. Filter to collect the precipitate and dissolve in water. Centrifuge to remove slag, take the supernatant alcohol precipitation (alcohol concentration 80%) 2-3 times, and collect 50 g of the precipitate—polysaccharide (HP).
Embodiment 3
[0074] Weigh 1Kg of the fruiting body of Hericium erinaceus, add 20Kg of water, and extract 3 times at 96°C for 1 hour each time. The extracts were combined, filtered, concentrated under reduced pressure and in vacuo, the thermal specific gravity was 1.06, and finely filtered. Add 2g of enzyme, adjust temperature to 35-60°C, pH value to 5-7, and hydrolyze protein. Finely filter, add edible ethanol to precipitate, and the final concentration reaches 60%. Filter, collect the precipitate, dissolve it in water, and repeat the alcohol precipitation 2-3 times, and collect the precipitate—polysaccharide (HP) 70g.
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