Application of curcumin for treating myodystrophy
A technology for muscular dystrophy and curcumin, which is applied in the fields of muscular system diseases, neuromuscular system diseases, and medical preparations containing active ingredients, etc., can solve the problems of large side effects, inconclusive effects, and inconspicuous effects, and achieve a good protective effect. , Enhance the activity of antioxidant enzymes, inhibit the formation of free radicals
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[0012] The curcumin is extracted from the crude drug turmeric with alkaline water, and then the curcumin is made into an oral agent; specifically, 10 g of the crude drug turmeric is added to 500 ml of 1% soda water, decocted to 200 ml, and the oral liquid is prepared.
[0013] Curcumin significantly reduces spontaneous muscle damage in DMD mice
[0014] Eight newborn mdx mice were randomly divided into two groups: control group and treatment group.
[0015] The control group was given intraperitoneal injection of 0.1ml PBS every other day starting from the 15th day after birth; while the treatment group was injected with 0.1ml curcumin (0.1mg) for 13 consecutive days. , organs and tissues were taken respectively, fixed in formalin, routinely embedded in paraffin for sectioning, and then histologically observed.
[0016] The results show:
[0017] 1. The protective effect of curcumin on the diaphragm of mdx mice
[0018] The mice in the control group had slight tissue damage...
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