Bioenergy muscle relexant

Abstract

The present invention is to utilize actin-myosin-adenosine triphosphatase inhibitor, diacetyl oxime and its isomer and analog as well as hydroxide medicinal components with the similar effect, as special muscle relaxing agent to remit paphological muscle hypertension and over contraction clinically. The mechanism of muscle relaxation is to inhibit the function of actin-myosin-adenosine triphosphatase, to baffle muscle from obtaining biological energy for contraction and thus to inhibit muscle's contraction. The present invention has certain effect to abnormal contraction of both smooth muscle and striated muscle. The pathological muscle hypertension and over contraction is found in asthma, hypertension, coronary blood vessel spasm, etc. The bioenergy muscle relaxing agent may be used clinically alone or as one kind of medicinal component.

Description

technical field [0001] The present invention relates to a pharmaceutical preparation containing organic active ingredients. Background technique [0002] Human muscle tissue originates from the mesoderm. During embryonic development, it gradually differentiates into three main muscle tissues, namely skeletal muscle, cardiac muscle and smooth muscle. [0003] Each muscle tissue has its own mechanism for producing contraction under normal physiological conditions or abnormal pathological conditions. [0004] Contraction of skeletal muscles. [0005] The contraction mechanism of skeletal muscle, generally speaking, goes through the following process: [0006] 1. The central nervous system sends nerve impulses along the efferent fibers of motor neurons to the nerve-muscle junction, that is, the motor end plate. [0007] 2. Nerve endings located in the motor endplate release a nerve mediator, namely acetylcholine (acetylcholine). [0008] 3. The released acetylcholine binds ...

AI Technical Summary

Problems solved by technology

But no studies have shown that BDM can be used to act on the muscle contractor mechanism