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Hawthorn leaves total flavone soft capsule and its preparing method

A technology of total flavonoids and hawthorn leaves, which is applied in the field of hawthorn leaf total flavonoids pharmaceutical preparations, can solve the problems of short development time of hawthorn leaves, etc., and achieve the effects of reducing the size of myocardial infarction, good stability, and convenient administration

Inactive Publication Date: 2004-11-24
张晴龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the short development time of hawthorn leaves in my country, the only available medicinal preparations of hawthorn leaves are tablets and capsules, which cannot meet the needs of the majority of patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Contents material composition: hawthorn leaf total flavonoids fine powder 50g, soybean oil 200g, beeswax 6g; capsule shell material composition: gelatin 200g, glycerin 81g, water 200g, paraffin methyl ester 0.04g, paraffin propyl ester 0.1g.

[0017] Preparation method: take beeswax and put it in soybean oil, heat it to melt, let it cool to room temperature, add total flavonoids of hawthorn leaves, stir well with a colloid mill to obtain the content; take gelatin, glycerin and water, put it in a suitable container and heat it to Dissolve at 80°C, filter, add methyl paraben and propyl paraben to the filtrate, mix well, keep warm at 60°C to obtain a rubber solution; take the above content and rubber solution, press them with soft capsule production equipment, and dry Afterwards, the total flavonoids of hawthorn leaf soft capsule of the present invention is obtained.

Embodiment 2

[0019] Content material composition: total flavonoids of hawthorn leaves 54g, peanut oil 200g, beeswax 7g; capsule shell material composition: gelatin 205g, glycerin 82g, water 200g, paraparkin methyl ester 0.05g, paraparkin ethyl ester 0.08g.

[0020] Preparation method: take beeswax and put it in soybean oil, heat it to melt, let it cool to room temperature, add total flavonoids of hawthorn leaves, stir well with a colloid mill to obtain the content; take gelatin, glycerin and water, put it in a suitable container and heat it to Dissolve at 80°C, filter, add paralyzed methyl ester and paralyzed ethyl ester to the filtrate, mix well, keep warm at 60°C to obtain a rubber solution; take the above content and rubber solution, press them with soft capsule production equipment, and dry Afterwards, the total flavonoids of hawthorn leaf soft capsule of the present invention is obtained.

[0021] Pharmacodynamic test

[0022] The purpose of the experiment was to observe the effects ...

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PUM

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Abstract

A haw leaf flavone softgel for preventing thrombosis, myocardial ischmie and myocardial infarction, and treating hypertension, hyperlipomia and coronary heart disease is composed of active component and soft shell. Said active component is prepared from haw leaf flavone, plant oil and beeswax. Said soft shell is prepared from gelatin, water, glycein and nipagin.

Description

Technical field [0001] The invention relates to a pharmaceutical preparation of total flavonoids from hawthorn leaves, more specifically, a soft capsule of total flavonoids from hawthorn leaves, and simultaneously the invention also relates to a preparation method of the preparation. Background technique [0002] Cardiovascular and cerebrovascular diseases are one of the diseases with a higher prevalence in the world. There are many factors that lead to cardiovascular and cerebrovascular diseases, among which hypertension, hyperlipidemia, oxidized low-density lipoprotein, and oxygen free radicals are all important factors. With the development of society and experience, and the improvement of people's living standards, the prevalence of cardiovascular diseases is also increasing year by year. According to relevant reports, it is conservatively estimated that there are more than 90 million hypertensive patients in my country, and the prevalence of diabetes accounts for 3% of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K31/7048A61P9/00A61P9/10
Inventor 张晴龙
Owner 张晴龙
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