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Application of Bougufuran in preparation of smoking cessation product

A technology of buguefuran and buguefuran is applied in the application field of buguefuran in the preparation of smoking cessation products, which can solve problems such as large side effects and incomplete smoking cessation, and achieve the effects of low toxic side effects, easy control of smoking addiction and broad market prospects.

Pending Publication Date: 2022-08-09
天津港保税区有维生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] For this reason, the present invention provides the application of Bugfuran in the preparation of smoking cessation products to solve the problems of existing smoking cessation products with large side effects and incomplete smoking cessation.

Method used

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  • Application of Bougufuran in preparation of smoking cessation product
  • Application of Bougufuran in preparation of smoking cessation product
  • Application of Bougufuran in preparation of smoking cessation product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 Application of Bouguerfuran in the e-liquid of electronic cigarette

[0029] Components: 10g of glycerin, 10g of 1,2-propanediol, 0.2g of Bugfuran, 0.3g of borneol, 0.2g of mint, and 0.2g of caffeine.

[0030] Preparation method: Weigh 10g of glycerol and 1,2-propanediol respectively, mix them evenly, add 0.2g of Bugfuran, stir evenly, add 0.3g of ground borneol, 0.2g of mint and 0.2g of caffeine, stir to dissolve, namely have to.

[0031] In this embodiment, the added mint and borneol and other ingredients can disperse wind-heat, clear the head and eyes, relieve the throat, reduce swelling and relieve pain. After mint enters the human body, it has an excitatory effect, can stimulate the central nervous system, indirectly conduct the peripheral nerves, and make the respiratory tract capillary. Dilates blood vessels and enhances the absorption of bougainvillea by the body.

[0032] The e-liquid obtained in Example 1 is directly added to the electronic cigaret...

Embodiment 2

[0033] The application of embodiment 2 Bugafuran in patch

[0034] The prescription is shown in Table 1:

[0035] Table 1 Prescription table of Bugfuran applied in patch

[0036]

[0037] Preparation method: Weigh 1 g of Bugfuran, 5 g of polyvinylpyrrolidone (K30), 93.9 g of acrylate pressure-sensitive adhesive, and 100 mg of DL-α-tocopherol, respectively, and add them to a mixed solution of 40 g each of ethanol and ethyl acetate, dissolve and stir. Evenly, let stand for defoaming, evenly coat 1000 pieces, and dry.

[0038] In this example, Bugfuran is prepared into a patch with a dosage of 1 mg / stick. During the smoking cessation process, it can be directly attached to the skin surface, 1-3 times a day, 2 patches each time.

Embodiment 3

[0039] The application of embodiment 3 Bouguerfuran in tablet

[0040] The prescription is shown in Table 2:

[0041] Table 2 Application prescription table of Bugfuran in tablet

[0042]

[0043] Preparation method: Weigh 150 g of PVP K30 and dissolve it in 1000 mL of 95% ethanol, add 15.0 g of Bugfuran, dissolve, shake well, and spray dry under nitrogen protection to obtain solid powder. Take all the solid powders, add 5 g of sodium carboxymethyl starch and 0.4 g of silicon dioxide, mix evenly, measure the content of bougainvillea, and press into tablets according to each tablet containing 15 mg of bougainvillea.

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Abstract

The invention discloses application of Bougufuran in preparation of smoking cessation products, and particularly relates to the field of medicine and health care. According to the application of the bugufuran in preparation of the smoking cessation product, the smoking cessation product comprises a smoking cessation medicine, and the smoking cessation medicine comprises the bugufuran and common pharmaceutical auxiliary materials. The raw material Bougufuran used in the invention is an agilawood furan compound, has a remarkable anti-anxiety effect and low toxic and side effects, and has a good control effect on withdrawal of nicotine addiction when being applied to the smoking cessation direction, so that a smoker can control the smoking addiction more easily, and has a certain inhibition effect on withdrawal reaction in the smoking cessation process; a better smoking cessation effect can be achieved, smoking cessation is thorough, and repeated smoking is avoided; the tobacco tar is applied to electronic cigarette tobacco tar, is a good substitute for nicotine, not only can eliminate or reduce neuro-dependence on nicotine, but also has no nicotine addiction, and also has good taste and smoke sense; meanwhile, the method can be widely applied to electronic atomization products to achieve the effects of soothing the nerves and resisting anxiety; the market prospect is wide.

Description

technical field [0001] The invention relates to the field of medicine and health care, in particular to the application of bougainvillea in the preparation of smoking cessation products. Background technique [0002] Agarwood is a traditional and precious traditional Chinese medicine. It is the wood heart containing precipitation resin that has been infected by fungi of the Thymelaeaceae (aquilaria) plant. "Shen Nong's Materia Medica" lists agarwood as the top grade. "Compendium of Materia Medica" records: Agarwood has the functions of clearing people's spirits, nourishing qi and combining spirits. There have been many reports on the chemical composition analysis of agarwood, mainly focusing on the study of agarwood essential oil. Six types of compounds have been reported by chemists at home and abroad, such as: benzyl acetone, hydrogenated cinnamic acid, agarwood alcohols, agarwood spiro rings and agarwood furans. [0003] Buagafuran, chemical name (1R,6S,9R)6,10,10-trime...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/343A23L33/10A61K36/534A24B15/167A61P25/34A61K31/045
CPCA61K31/343A61K31/045A61K36/534A61P25/34A23L33/10A24B15/167A23V2002/00A61K2300/00A23V2200/334A23V2200/31Y02A50/30
Inventor 石宏宇洪源张成龙
Owner 天津港保税区有维生物科技有限公司
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