Super-resolution imaging system and imaging method based on micro-bottle lens

Abstract

The super-resolution imaging system based on the micro-bottle lens comprises a micro-bottle lens module, a position control module and an optical microscope, the micro-bottle lens module comprises the micro-bottle lens, and the position control module can control the micro-bottle lens to rotate. A to-be-imaged sub-diffraction limit scale sample is mounted on an objective table of the optical microscope, the micro-bottle lens is arranged above the sample, and super-resolution imaging can be performed on the to-be-imaged sub-diffraction limit scale sample by utilizing the micro-bottle lens and the optical microscope. According to the super-resolution imaging system provided by the invention, non-contact, lossless and pollution-free imaging of a sample lower than a diffraction limit scale can be realized by utilizing the dielectric micro-bottle lens and combining a conventional optical microscope. In addition, the invention also provides a super-resolution imaging method based on the micro-bottle lens.

Description

technical field [0001] The present application relates to the technical field of optical imaging, and in particular, to a super-resolution imaging system and imaging method based on a micro bottle lens. Background technique [0002] In the process of exploring, discovering and understanding nature, optical imaging technology plays an important role. The super-resolution optical imaging technology, which has the ability to break through the diffraction limit, can deepen the tentacles of scientific activities to the "nano" scale, so that the microscopic information of macroscopic objects can be more accurately recognized, understood and revealed. Microparticle lens-assisted super-resolution optical imaging technology is an emerging research field in recent years. It realizes super-resolution imaging through the combination of conventional optical microscopes and microparticle lenses. , the device structure is simple and no additional sample preparation is required. So far, p...

AI Technical Summary

Problems solved by technology

[0004] The existing particle lens-assisted super-resolution imaging technology uses spherical and cylindrical particle lenses. The tightly focused beam formed by this type of particle lens under illumination has a small focal length and a short working distance, and it is easy to come into contact with the sample or friction, causing difficulty in scanning imaging and contamination or damage to the sample, and the operation process becomes relatively slow and uncontrollable

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