Micro-fluidic chip and control method and analysis device thereof

Abstract

The invention provides a micro-fluidic chip, a control method thereof and an analysis device. The micro-fluidic chip comprises: a micro-fluidic channel; and the micro-strip antenna array is provided with a plurality of micro-strip antennas, the plurality of micro-strip antennas are arranged at intervals along the flowing direction of the micro-droplets, and the micro-strip antennas can emit microwave signals. The microwave signal is used for at least one of determining the position of the micro-droplet, determining the size of the micro-droplet and analyzing components in the micro-droplet. The micro-fluidic chip is simple in structure, can accurately position the micro-droplets in the micro-fluidic channel, can also measure the sizes of the micro-droplets and detect predetermined components in the micro-droplets, further can realize direct transmission of detection signals, and is good in signal uniformity, high in detection efficiency, high in accuracy, strong in detection flexibility and small in measurement error.

Description

technical field [0001] The present invention relates to the technical field of microfluidics, in particular, to a microfluidic chip, a control method thereof, and an analysis device. Background technique [0002] At present, microfluidic technology has broad application prospects in gene sequencing, biomedical diagnosis and detection. It can integrate basic operation units such as sample preparation, reaction, separation, and detection in biological, chemical, and medical analysis processes into a micron scale on a microfluidic chip. However, when the microfluidic chip in the related art realizes the detection of the sample (for example, the position detection, size detection and detection of the components in the microdroplet, etc.) (such as microscopes, spectrometers, etc.), which is not conducive to the integrated development of microfluidic chips. More importantly, for optical detection methods such as microscopes and spectrometers, due to the optical path design, the ...

AI Technical Summary

Problems solved by technology

However, when the microfluidic chip in the related art realizes the detection of the sample (such as the detection of the position of the microdroplet, the detection of the size and the detection of the components in the microdroplet, etc.), it generally needs to rely on external devices that are separate from the microfluidic chip. (such as microscopes, spectrometers, etc.), which is not conducive to the integrated development of microfluidic chips

More importantly, for optical detection methods such as microscopes and spectrometers, the number of samples that can be detected and the flexibility of detection are limited due to the design of the optical path, and the intensity of the excitation light signal is uneven and the position is not accurate, which leads to the accuracy of the detection results. lower

[0003] Therefore, the related technologies of existing microfluidic chips still need to be improved.

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