Low-temperature preservation box for deciduous tooth pulp stem cells

Abstract

The deciduous tooth pulp stem cell low-temperature preservation box comprises a bottom plate, a lifting mechanism is arranged on the upper surface of the bottom plate, a box body is arranged on the outer side of the lifting mechanism, the lower side of the box body is fixedly connected with the position, close to the side edge, of the upper surface of the bottom plate, and a preservation box body is connected to the upper side of the lifting mechanism. An opening matched with the preservation box is formed in the upper side wall of the box body, a mounting cavity is formed in the left side of the interior of the preservation box, a refrigeration mechanism is arranged in the mounting cavity, a storage cavity is formed in the right side of the interior of the preservation box, a placement frame is arranged in the storage cavity, and a plurality of test tube insertion openings are formed in the placement frame; the upper side of the storage cavity is provided with a cover body, the cover body is slidably mounted on the upper side of the storage cavity, the height of the storage box can be adjusted, so that the device is suitable for doctors with different heights, the doctors can work more conveniently, meanwhile, the refrigeration mechanism refrigerates the interior of the mounting cavity, and it is guaranteed that teeth are stored in a low-temperature state.

Description

Technical field [0001] The present invention relates to the field of cryopreservation box technology, the specific field is a kind of deciduous tooth pulp stem cell cryopreservation box. Background [0002] With the wide application of clinical practice, pulp stem cells in the restoration of pulp activity and regeneration of teeth and other aspects of greater progress is predictable, people's functional awareness of pulp stem cells is also getting higher and higher, pulp tissue is located in the pulp cavity inside the teeth, is the only soft tissue in the tooth tissue, through the study of human pulp cells, found a very similar to the bone marrow mesenchymal stem cells have a very similar immune phenotype and the ability to form mineralized nodules, the cell morphology is spindle-shaped, self-renewal and multi-directional differentiation, Has a strong cloning ability. These fibroblast cells isolated from the pulp tissue are called pulp stem cells, pulp stem cells have the potenti...

AI Technical Summary

Problems solved by technology

These fibroblasts isolated from dental pulp tissue are called dental pulp stem cells. Dental pulp stem cells have the potential of multi-directional differentiation. In addition to cells capable of forming mineralized nodules, they are induced by different cytokines. It can also be differentiated into fat, bone, cartilage, muscle, vascular endothelium, liver, nerve and other cell line types. The Fourth Military Medical University of China has carried out clinical trials to use autologous stem cells from deciduous teeth for regeneration treatment of dental pulp necrosis. At present, more and more clinical trials have confirmed the therapeutic effect of stem cells. Since dental pulp stem cells have the ability to differentiate into multiple directions, they can be used to help repair teeth, joints, and nerves with damaged heart valves in the future. For the extraction of stem cells There is a requirement for activity. After getting the examined deciduous teeth, the most important step is to quickly put the extracted teeth into a low-temperature environment within 7 seconds to maintain the internal activity of the teeth. Overtime is useless, but most of the current low-temperature storage The transport box has a simple structure and is inconvenient for doctors to operate. Therefore, a low-temperature preservation box for deciduous dental pulp stem cells is proposed.

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