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Application of Ly6d in diagnosis, prognosis monitoring and treatment of pancreatic ductal adenocarcinoma

A pancreatic cancer and prognosis technology, applied in the field of biomedicine, can solve the problems of poor prognosis of patients

Pending Publication Date: 2022-04-05
RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3) Through tissue chip staining, the prognosis of patients with high expression of LY6D in human pancreatic tumors is worse

Method used

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  • Application of Ly6d in diagnosis, prognosis monitoring and treatment of pancreatic ductal adenocarcinoma
  • Application of Ly6d in diagnosis, prognosis monitoring and treatment of pancreatic ductal adenocarcinoma
  • Application of Ly6d in diagnosis, prognosis monitoring and treatment of pancreatic ductal adenocarcinoma

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Embodiment Construction

[0017] In order to make the present invention more obvious and understandable, the preferred embodiments are described in detail as follows in conjunction with the accompanying drawings:

[0018] The invention provides the application of LY6D in preparing a diagnostic reagent for diagnosing pancreatic cancer, the application includes detecting the serum concentration of LY6D.

[0019] The invention provides the application of LY6D in the preparation of a diagnostic reagent for monitoring the progression of pancreatic cancer, and the application includes detecting the serum concentration of LY6D.

[0020] The invention provides the application of LY6D in the preparation of a diagnostic reagent for evaluating the prognosis of pancreatic cancer, and the application includes detecting the serum concentration of LY6D.

[0021] The invention provides the application of LY6D in the preparation of medicine for treating pancreatic cancer.

[0022] The above applications include the pr...

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Abstract

The invention relates to application of LY6D in diagnosis, prognosis monitoring and treatment of pancreatic ductal adenocarcinoma, and belongs to the technical field of biological medicine. The invention provides an application of LY6D in preparation of a diagnostic reagent for diagnosing pancreatic cancer and an application of LY6D in preparation of a diagnostic reagent for monitoring disease progression of pancreatic cancer. The application comprises the following steps: detecting serum concentration and histological expression level of LY6D; the invention also discloses an application of LY6D in preparation of drugs for treating pancreatic cancer.

Description

technical field [0001] The invention relates to the application of Ly6d in the diagnosis, prognosis monitoring and treatment of pancreatic ductal adenocarcinoma, belonging to the technical field of biomedicine. Background technique [0002] Pancreatic ductal adenocarcinoma (PDAC), a deadly malignancy, ranks as the third leading cause of cancer-related death in Western countries and is expected to become the second leading cause of cancer after lung cancer by 2030 related cause of death. The 5-year survival rate of patients with pancreatic ductal adenocarcinoma remains less than 10% due to the lack of reliable early biomarkers and poor response to chemotherapy and targeted therapy. Pancreatic cancer lacks specific symptoms in the early stage, and its clinical diagnosis mainly relies on imaging examinations (including enhanced CT, magnetic resonance imaging, and endoscopic ultrasound) combined with tissue biopsy pathology. About 70% occur in the head of the pancreas and usua...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/574G01N33/68A61K45/00A61P35/00
Inventor 薛婧石娟娟唐莹莹路平
Owner RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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