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Traditional Chinese medicine composition for treating thyroid cancer and preparation method thereof

A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, pharmaceutical formulation, drug delivery, etc., can solve the problems of long course of treatment, high toxicity of chemotherapy drugs, high cost, and achieve the effect of inhibiting value-added

Active Publication Date: 2022-03-15
ZHEJIANG PROVINCIAL PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chemotherapy drugs are highly toxic. While killing tumor cells, they also non-selectively kill white blood cells, lymphocytes and other human immune cells. As a result, patients often suffer from infection due to low autoimmunity. High, with great limitations in clinical use

Method used

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  • Traditional Chinese medicine composition for treating thyroid cancer and preparation method thereof
  • Traditional Chinese medicine composition for treating thyroid cancer and preparation method thereof
  • Traditional Chinese medicine composition for treating thyroid cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of embodiment 1 oral liquid

[0034] Astragalus 1.5kg Atractylodes macrocephala 0.9kg Poria cocos 0.9kg

[0035] Paeoniae Alba 0.9kg, Southern Star 0.9kg, Fritillaria 0.9kg

[0036] Pinellia 0.9kg Wood Butterfly 0.9kg Prunella vulgaris 0.9kg

[0037] A. Take 9 raw medicinal materials of Astragalus, Atractylodes macrocephala, Poria cocos, Radix Paeoniae Alba, Zhinanxing, Fritillary Fritillaria, Pinellia, Orchid Butterfly, and Prunella vulgaris, among which Astragalus, Atractylodes macrocephala, Poria cocos, Radix Paeoniae Alba, and Radix Paeoniae Alba are cleaned and sliced. Fritillaria, pinellia coarsely chopped, Prunella vulgaris cut into sections, wood butterflies cleaned, set aside;

[0038] B. Weigh the herbal medicine pieces of raw materials in step A according to the prescription amount, mix well, and decoct twice. For the first time, add 8 times the amount of water to decoct for 3 hours, and for the second time, add 6 times the amount of water t...

Embodiment 2

[0041] The preparation of embodiment 2 mixture

[0042] Astragalus 2.0kg Atractylodes macrocephala 0.5kg Poria cocos 1.5kg

[0043] Paeoniae Alba 0.5kg Southern Star 1.5kg Fritillaria 0.5kg

[0044] Pinellia 1.5kg Wood Butterfly 0.6kg Prunella vulgaris 1.5kg

[0045] A. Take 9 raw medicinal materials of Astragalus, Atractylodes macrocephala, Poria cocos, Radix Paeoniae Alba, Zhinanxing, Fritillary Fritillaria, Pinellia, Orchid Butterfly, and Prunella vulgaris, among which Astragalus, Atractylodes macrocephala, Poria cocos, Radix Paeoniae Alba, and Radix Paeoniae Alba are cleaned and sliced. Fritillaria, pinellia coarsely chopped, Prunella vulgaris cut into sections, wood butterflies cleaned, set aside;

[0046] B. Weigh the medicinal herbal pieces of step A according to the prescription amount, mix them evenly, and decoct twice. For the first time, add 10 times the amount of water to decoct for 2 hours, and for the second time, add 8 times the amount of water to decoct for 1...

Embodiment 3

[0049] The preparation of embodiment 3 granules

[0050] Astragalus 1.5kg Atractylodes macrocephala 0.9kg Poria cocos 0.9kg

[0051] Paeoniae Alba 0.9kg, Southern Star 0.9kg, Fritillaria 0.9kg

[0052] Pinellia 0.9kg Wood Butterfly 0.9kg Prunella vulgaris 0.9kg

[0053] A. Take 9 raw medicinal materials of Astragalus, Atractylodes macrocephala, Poria cocos, Radix Paeoniae Alba, Zhinanxing, Fritillary Fritillaria, Pinellia, Orchid Butterfly, and Prunella vulgaris, among which Astragalus, Atractylodes macrocephala, Poria cocos, Radix Paeoniae Alba, and Radix Paeoniae Alba are cleaned and sliced. Fritillaria, pinellia coarsely chopped, Prunella vulgaris cut into sections, wood butterflies cleaned, set aside;

[0054] B. Weigh the medicinal herbal pieces of step A according to the prescription amount, mix well, and decoct twice, add 10 times the amount of water for decoction for 3 hours for the first time, add 8 times the amount of water for decoction for 1 hour for the second t...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating thyroid cancer and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following nine raw medicinal materials: astragalus membranaceus, bighead atractylodes rhizome, poria cocos, white paeony root, prepared arisaema consanguineum schott, thunberg fritillary bulb, pinellia ternate, oroxylum indicum and selfheal, and has the effects of invigorating spleen and replenishing qi, eliminating dampness and phlegm, and softening hardness to dissipate stagnation. Pharmacodynamic experiment results show that the traditional Chinese medicine composition disclosed by the invention can obviously inhibit the growth of human thyroid cancer tumors in nude mice bearing tumors and obviously inhibit the proliferation of thyroid cancer cells in vitro, has an exact treatment effect on thyroid cancer, and provides a new clinical medication choice for patients.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating thyroid cancer and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Thyroid cancer is the most common malignant tumor of the thyroid gland. In recent years, the incidence of thyroid cancer has increased significantly, especially in coastal cities. Young adults are a high-risk group for thyroid cancer, and there are more women than men, with a male to female ratio of 1:3. The reason why there are more women than men in thyroid cancer is related to the physiological functions of the thyroid gland. [0003] In the early stage of thyroid cancer, there are usually no obvious symptoms, only a mass appears in the thyroid tissue, which often gradually increases, the surface is uneven, the texture is hard, and the up and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61P35/00
CPCA61K36/481A61K36/284A61K36/076A61K36/71A61K36/65A61K36/8884A61K36/8966A61K36/8888A61K36/185A61K36/536A61K9/0053A61P35/00A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 葛明华谭卓李清林黄萍潘宗福徐加杰刘宇佳
Owner ZHEJIANG PROVINCIAL PEOPLES HOSPITAL
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