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Repair dressing containing ginseng extract and preparation method thereof

A technology of ginseng extraction and plant extract, applied in medical science, bandages, etc., can solve the problems of unguaranteed antibacterial properties, easy shedding, physical doping, etc., and achieve excellent water retention and moisturizing properties, reasonable process design, and high practicability Effect

Active Publication Date: 2021-12-31
蓝科医美科学技术(吉林)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the deepening of the research, we found that in order to improve the antibacterial performance of the gel dressing, antibacterial particles are generally added to the gel in the prior art, but the pure physical doping is used to cover it with the gel. Easy to fall off, the actual antibacterial performance cannot be guaranteed

Method used

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  • Repair dressing containing ginseng extract and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0038] A preparation method of a repair dressing containing ginseng extract, comprising the following steps:

[0039] (1) Take starch, add 2mL sodium hydroxide, stir and mix for 20min, basify at -18°C for 20h, let stand to thaw, then transfer to 50mL ethanol solution, stir and disperse for 1h, add trisodium and benzyl ammonium chloride (catalyst ), continue stirring for 10 minutes, add 2-chloroethylamine hydrochloride, stir and react for 18 hours, collect the product by filtration, wash, and freeze-dry to obtain modified starch; the mass ratio of starch to 2-chloroethylamine hydrochloride is 1:2 .

[0040] (2) Get chitosan and acetic acid solution, mix and stir to obtain a mixed solution, the mass concentration of the mixed solution is 2.5%, spray the mixed solution into the sodium polyphosphate solution, react for 4h, get the precipitated beads, transfer to sodium hydroxide Swell in the solution, then add epichlorohydrin solution, continue to react for 24 hours, wash until n...

Embodiment 2

[0051] A preparation method of a repair dressing containing ginseng extract, comprising the following steps:

[0052] (1) Take starch, add 2mL sodium hydroxide, stir and mix for 25min, basify at -18°C for 21h, let stand to thaw, then transfer to 50mL ethanol solution, stir and disperse for 1.2h, add trisodium and benzyl ammonium chloride ( Catalyst), continue to stir for 15min, add 2-chloroethylamine hydrochloride, stir and react for 19h, filter and collect the product, wash, and freeze-dry to obtain modified starch; the mass ratio of starch to 2-chloroethylamine hydrochloride is 1: 2.

[0053] (2) Get chitosan and acetic acid solution, mix and stir to obtain a mixed solution, the mass concentration of the mixed solution is 2.5%, spray the mixed solution into the sodium polyphosphate solution, react for 4.5h, take the precipitated beads, and transfer to the hydroxide Swell in sodium solution, then add epichlorohydrin solution, continue to react for 25 hours, wash until neutra...

Embodiment 3

[0064] A preparation method of a repair dressing containing ginseng extract, comprising the following steps:

[0065] (1) Take starch, add 2mL sodium hydroxide, stir and mix for 30min, basify at -18°C for 22h, let stand to thaw, then transfer to 50mL ethanol solution, stir and disperse for 1.5h, add trisodium and benzyl ammonium chloride ( catalyst), continue to stir for 20min, add 2-chloroethylamine hydrochloride, stir and react for 20h, filter and collect the product, wash, and freeze-dry to obtain modified starch; the mass ratio of starch to 2-chloroethylamine hydrochloride is 1: 2.

[0066] (2) Get chitosan and acetic acid solution, mix and stir to obtain a mixed solution, the mass concentration of the mixed solution is 2.5%, spray the mixed solution into the sodium polyphosphate solution, react for 4.5h, take the precipitated beads, and transfer to the hydroxide Swell in sodium solution, then add epichlorohydrin solution, continue to react for 26 hours, wash until neutra...

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Abstract

The invention discloses a repair dressing containing a ginseng extract and a preparation method thereof. The repair dressing with excellent antibacterial performance containing the ginseng extract is prepared from the following main components: functional chitosan, oxidized sodium alginate, chitosan microspheres, and plant extracts. Functional chitosan and oxidized sodium alginate are used as main components to prepare hydrogel that is of a porous reticular shape as a whole, conducive to slow release effect of chitosan microspheres and plant extracts. The repair dressing comprises plant extracts including a ginseng extract and a centella asiatica extract that facilitate skin absorption on the one hand and achieves anti-inflammatory and antibacterial effects on the other hand, thereby improving antibacterial performance of the repair dressing and avoiding wound inflammation. The repair dressing is reasonable in process design, and the prepared repair dressing not only has excellent antibacterial performance, but also has excellent water retention and moisture retention performance, and can effectively promote wound repair.

Description

technical field [0001] The invention relates to the technical field of dressings, in particular to a repairing dressing containing ginseng extract and a preparation method thereof. Background technique [0002] Hydrogel dressing is one of the more common dressings on the market. It is generally suitable for repairing wounds such as epidermal defect wounds and painful wounds. Hydrogel dressings can provide a moist environment for wounds to promote wound healing. At the same time, it can absorb wound exudate and relieve wound pain on the wound surface. [0003] With the deepening of the research, we found that in order to improve the antibacterial performance of the gel dressing, antibacterial particles are generally added to the gel in the prior art, but it is simply physically doped and covered by the gel. It is easy to fall off, and the actual antibacterial performance cannot be guaranteed. [0004] Based on the above situation, we disclose a repair dressing containing gi...

Claims

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Application Information

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IPC IPC(8): A61L26/00C08B31/12
CPCA61L26/008A61L26/0085A61L26/0057A61L26/0023A61L26/0033A61L26/0066C08B31/125A61L2300/602A61L2300/45A61L2300/41A61L2300/404A61L2300/412A61L2300/252A61L2300/30C08L5/04C08L5/08C08L3/02
Inventor 曹原眭春徐阳
Owner 蓝科医美科学技术(吉林)有限公司
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