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Ultrasonic imaging method and device

An ultrasonic imaging method and ultrasonic image technology, which are applied in ultrasonic/sonic/infrasonic diagnosis, sonic diagnosis, infrasonic diagnosis, etc., can solve problems such as inability to track magnetic nanoparticles in real time with high signal-to-noise ratio, and achieve the effect of avoiding background interference.

Pending Publication Date: 2021-11-05
NANJING TRANSCEND VIVOSCOPE BIO TECH CO LTD
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Problems solved by technology

However, traditional optical imaging, magnetic resonance imaging, and ultrasound imaging cannot achieve high signal-to-noise ratio real-time tracking of magnetic nanoparticles in deep tissues (such as greater than 5 cm).

Method used

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  • Ultrasonic imaging method and device
  • Ultrasonic imaging method and device

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Embodiment Construction

[0028] The target area referred to in this application may be the area to be imaged. The target area may be, for example, some tissue of a human body or an animal body, such as the lungs of a human body, or the liver of an animal. As an example, the target area may be deep tissue, such as the tissue where cancer cells are located.

[0029] Magnetic nanoparticles are nanoscale particles, and their magnetic cores are generally composed of magnetic metal oxides such as iron, cobalt, and nickel. Magnetic nanoparticles are widely used in the field of targeted delivery of anti-tumor drugs due to their advantages of high permeability, magnetic guidance and long retention effect.

[0030] In order to better realize human-controlled drug delivery, the surface of magnetic nanoparticles usually needs to be modified. As an example, the modification can be directly wrapping the magnetic nanoparticles with organic or inorganic materials, so as to realize the functionalization of the magne...

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Abstract

The application discloses an ultrasonic imaging method and device. The method comprises the steps: gathering magnetic particles into a target region by using an external magnetic field; activating the magnetic particles in the target region by using an external alternating magnetic field so as to enable the magnetic particles to generate an ultrasonic signal; detecting the ultrasonic signal of the target region; and generating an ultrasonic image of the target region by using the ultrasonic signal. According to the technical scheme, the magnetic particles in the target region are activated by utilizing the external alternating magnetic field so as to enable the magnetic particles to generate the ultrasonic signal, thereby implementing high-signal-to-noise-ratio real-time tracing on the magnetic particles in deep tissues through ultrasonic imaging.

Description

technical field [0001] The present application relates to the field of ultrasound imaging, in particular to an ultrasound imaging method and device. Background technique [0002] Magnetic nanoparticles are widely used in the field of targeted delivery of anticancer drugs due to their high permeability and long retention effect. [0003] In the field of targeted delivery of antitumor drugs, real-time tracking of magnetic nanoparticles is a key technology to achieve artificially controlled drug delivery. However, traditional optical imaging, magnetic resonance imaging, and ultrasound imaging cannot achieve high signal-to-noise ratio real-time tracking of magnetic nanoparticles in deep tissues (eg, greater than 5 cm). Therefore, how to realize real-time tracking of magnetic nanoparticles in deep tissues with high signal-to-noise ratio is an urgent technical problem to be solved. Contents of the invention [0004] The present application provides an ultrasonic imaging method...

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Application Information

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IPC IPC(8): A61B8/00
CPCA61B8/4411A61B8/481
Inventor 黄硕郭雯雨张珏
Owner NANJING TRANSCEND VIVOSCOPE BIO TECH CO LTD
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