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A kind of sunscreen composition with high uva protective effect and application thereof

The technology of a composition and an ultraviolet absorber is applied in the directions of medical preparations containing active ingredients, preparations for skin care, preparations for dressing, etc. To achieve the best protection effect, efficient defense effect

Active Publication Date: 2022-08-02
宝萃生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the vast majority of crystalline sunscreens have poor solubility in common oil components. The highest solubility ratio of crystalline sunscreens in oil is 0.28:1, and they are easy to recrystallize from their solutions. Patent US6423302B1 uses octocrylene to dilute - The solubility of ethylhexylphenol methoxyphenyl triazine is improved, but the system also uses a large amount of oil to assist in dissolution. Excessive use of oil will increase the cost, resulting in poor skin feel, and it is easy to rub mud on the skin surface , and lead to system instability

Method used

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  • A kind of sunscreen composition with high uva protective effect and application thereof
  • A kind of sunscreen composition with high uva protective effect and application thereof
  • A kind of sunscreen composition with high uva protective effect and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Example 1 Sunscreen composition with high UVA protection

[0058] 1, the present embodiment provides a series of sunscreen compositions with high UVA protection effect, and the specific components and recipe consumption are as shown in table 1 and table 2:

[0059] Table 1

[0060]

[0061]

[0062] Table 2

[0063]

[0064] 2. The preparation methods of compositions 1-12 are as follows:

[0065] S1. Weigh crystalline UVA ultraviolet absorber, UVB ultraviolet absorber and oil and mix;

[0066] S2. Heating at 80~85°C for 5~15min, dissolving until clear and transparent, cooling to 40~45°C to obtain the sunscreen composition.

experiment example 1

[0081] 1. Experimental method The stability of the compositions 1-12 in Example 1 and the compositions in Comparative Examples 1-9 was investigated. The specific method was to place the prepared compositions at 5°C and -18°C for 1 month. , observe its precipitation.

[0082] 2. Experimental results

[0083] table 5

[0084]

[0085]

[0086] Compositions 1-12 and Comparative Examples 1-9 were placed in an environment of 5° C. and -18° C. for 1 month, and their product states were shown in Table 5. It can be seen from the results in Table 5 that the raw materials according to the present invention were The sunscreen composition prepared by proportioning has no crystallization, which shows that the crystalline UVA ultraviolet absorber can be stably dissolved in lipid, and changes the consumption of the crystalline UVA ultraviolet absorber, UVB ultraviolet absorber, and grease or the type of grease ( Comparative examples 1-9) may lead to a decrease in the solubility of th...

experiment example 2

[0089] Experimental example 2 SPF value and UVA value test

[0090] 1. Experimental method

[0091] With reference to ISO24444 and ISO 24443, the compositions 1-12 in Example 1 and the composition samples of Comparative Example 3 were tested for SPF value and UVA value.

[0092] Instrument: Labsphere 2000; Carrier: PMMA (Roughness 6μm, Helioscreen); application amount 1.3mg / cm 2 .

[0093] 3. Experimental results

[0094] Table 6

[0095] combination SPF UVA-PF combination SPF UVA-PF Composition 1 30.8 24.6 Composition 8 30 23.7 Composition 2 32.9 20.4 Composition 9 38.5 22 Composition 3 35.1 20.9 Composition 10 30.9 20.3 Composition 4 38.7 21.7 Composition 11 30.4 21.2 Composition 5 34 20.1 Composition 12 34.9 20.1 Composition 6 30.5 23.6 Comparative Example 3 17.9 14.04 Composition 7 37.9 20.1

[0096] It can be seen from the experimental results in Table 6 that the sun...

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Abstract

The present invention provides a sunscreen composition with high UVA protection effect and application thereof. By compounding specific types of crystalline UVA ultraviolet absorbers, UVB ultraviolet absorbers, and oils, and controlling the proportions of the three components, the sunscreen composition obtained can achieve the maximum dissolution of the crystalline UVA ultraviolet absorbers, and the composition The UVA‑PF value reaches 20 and above, and the SPF value reaches 30 or above, which can simultaneously achieve high-efficiency skin protection against UVA and UVB, ensuring better UV protection effect.

Description

technical field [0001] The invention belongs to the technical field of daily cosmetics, and more particularly, relates to a sunscreen composition with high UVA protection effect and application thereof. Background technique [0002] In order to protect the skin from UV rays, sunscreen products, especially those with added sunscreen agents, are essential. In recent years, consumer demand for sunscreen products has also increased. Solar radiation contains about 5% ultraviolet (UV) radiation, and its wavelength is 200-400nm, which is divided into: 320-400nm (UV-A), 290-320 nm (UV-B) and 200-290nm (UV-C) ), where most of the UV-C radiation is absorbed by the ozone layer; UVA doses fluctuate in the range of 48-52% throughout the year; while UVB doses vary seasonally, reaching as high as 79% in summer and remaining at 29% in the rest of the season. Scientific research shows that the damage of UVB to the skin stays in the epidermis layer, while the damage of UVA to the skin can re...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/41A61K8/49A61K8/35A61K8/37A61K8/40A61K8/895A61Q17/04
CPCA61K8/411A61K8/4966A61K8/35A61K8/37A61K8/40A61K8/4946A61K8/895A61Q17/04A61K2800/592
Inventor 曾茜刘露刘逸华贺青
Owner 宝萃生物科技有限公司
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