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Sunscreen composition with high UVA protection effect and application thereof

A technology of a composition and an ultraviolet absorber, which is applied in the directions of medical preparations containing active ingredients, preparations for skin care, preparations for dressing, etc., can solve the problems of easy rubbing, unstable system, poor solubility, etc. The effect of resisting, the best protection effect

Active Publication Date: 2021-10-29
宝萃生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the vast majority of crystalline sunscreens have poor solubility in common oil components. The highest solubility ratio of crystalline sunscreens in oil is 0.28:1, and they are easy to recrystallize from their solutions. Patent US6423302B1 uses octocrylene to dilute - The solubility of ethylhexylphenol methoxyphenyl triazine is improved, but the system also uses a large amount of oil to assist in dissolution. Excessive use of oil will increase the cost, resulting in poor skin feel, and it is easy to rub mud on the skin surface , and lead to system instability

Method used

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  • Sunscreen composition with high UVA protection effect and application thereof
  • Sunscreen composition with high UVA protection effect and application thereof
  • Sunscreen composition with high UVA protection effect and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Example 1 Sunscreen composition with high UVA protection effect

[0058] 1. The present embodiment provides a series of sunscreen compositions with high UVA protective effect, and the dosage of specific components is as shown in Table 1 and Table 2:

[0059] Table 1

[0060]

[0061]

[0062] Table 2

[0063]

[0064] 2. The preparation method of compositions 1-12 is as follows:

[0065] S1. Take by weighing crystalline UVA ultraviolet absorber, UVB ultraviolet absorber and grease and mix;

[0066] S2. Heat at 80-85°C for 5-15 minutes, dissolve until clear and transparent, and cool down to 40-45°C to obtain the sunscreen composition.

experiment example 1

[0081] 1. Experimental method The stability of the compositions 1-12 in Example 1 and the compositions of Comparative Example 1-9 were investigated. The specific method was to place the prepared compositions at 5°C and -18°C for 1 month , observe its precipitation.

[0082] 2. Experimental results

[0083] table 5

[0084]

[0085]

[0086] Compositions 1-12 and Comparative Example 1-9 compositions were placed under 5°C and -18°C environments for 1 month, and their product status is shown in Table 5. As can be seen from the results in Table 5, according to the raw materials of the present invention The sunscreen composition prepared by proportioning has no crystallization, which shows that the crystalline UVA ultraviolet absorber can be stably dissolved in the lipid, and changes the amount of crystalline UVA ultraviolet absorber, UVB ultraviolet absorber, and oil or the type of oil ( Comparative Examples 1-9), all may lead to a decrease in the solubility of the crystal...

experiment example 2

[0089] Experimental example 2 SPF value and UVA value test

[0090] 1. Experimental method

[0091] With reference to ISO24444, ISO 24443, SPF value and UVA value test are carried out to composition 1-12 in embodiment 1 and comparative example 3 composition sample.

[0092] Instrument: Labsphere 2000; Carrier: PMMA (Roughness 6μm, Helioscreen); Smearing amount 1.3mg / cm 2 .

[0093] 3. Experimental results

[0094] Table 6

[0095] combination SPF UVA-PF combination SPF UVA-PF Composition 1 30.8 24.6 Composition 8 30 23.7 Composition 2 32.9 20.4 Composition 9 38.5 22 Composition 3 35.1 20.9 Composition 10 30.9 20.3 Composition 4 38.7 21.7 Composition 11 30.4 21.2 Composition 5 34 20.1 Composition 12 34.9 20.1 Composition 6 30.5 23.6 Comparative example 3 17.9 14.04 Composition 7 37.9 20.1

[0096] As can be seen from the experimental results in Table 6, the SPF value of th...

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Abstract

The invention provides a sunscreen composition with a high UVA protection effect and application thereof. By compounding specific types of crystalline UVA ultraviolet absorbent, UVB ultraviolet absorbent and grease and controlling the ratio of the three components, the obtained sunscreen composition can realize maximum dissolution of the crystalline UVA ultraviolet absorbent; the UVA-PF value of the composition reaches 20 or above; the SPF value reaches 30 or above; efficient resistance of skin to UVA and UVB can be realized at the same time; and a better ultraviolet protection effect is ensured.

Description

technical field [0001] The invention belongs to the technical field of daily cosmetics, more specifically, relates to a sunscreen composition with high UVA protection effect and application thereof. Background technique [0002] In order to protect the skin from ultraviolet rays, sunscreen products, especially those containing sunscreen agents, are indispensable, and consumer demand for sunscreen products has also increased in recent years. Solar radiation contains about 5% of ultraviolet (UV) radiation, its wavelength is 200-400nm, specifically divided into: 320-400nm (UV-A), 290-320nm (UV-B) and 200-290nm (UV-C ), where most of the UV-C radiation is absorbed by the ozone layer; throughout the year, the UVA dose fluctuates in the range of 48-52%; while the UVB dose varies seasonally, up to 79% in summer and 29% in the rest of the season. Scientific research shows that the damage of UVB to the skin stays in the epidermis, while the damage of UVA to the skin can go directly ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/41A61K8/49A61K8/35A61K8/37A61K8/40A61K8/895A61Q17/04
CPCA61K8/411A61K8/4966A61K8/35A61K8/37A61K8/40A61K8/4946A61K8/895A61Q17/04A61K2800/592
Inventor 曾茜刘露刘逸华贺青
Owner 宝萃生物科技有限公司
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